Radioactive therapy shows promise for kids with neuroblastoma

NCT ID NCT03966651

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested a radioactive drug called 177Lu-DOTATATE in one child with neuroblastoma that had come back or not responded to standard treatments. The drug targets tumor cells that have a specific marker (somatostatin receptors). The goal was to find a safe dose. The study is complete, but results are not yet available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

177Lu-DOTATATE (a radioactive drug that targets tumor cells)

What this could lead to

If it works, this could point toward a new treatment option for children with hard-to-treat neuroblastoma.

What could go wrong

This is a very early phase 1 trial with only 1 participant, so safety and effectiveness are not yet known. The treatment involves radiation, which carries risks like damage to healthy organs.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neuroblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Angers

    Angers, France

  • CHU Besançon

    Besançon, France

  • CHU Dijon

    Dijon, France

  • CHU Nancy

    Nancy, France

  • CHU Nantes

    Nantes, France

  • CHU Pellegrin

    Bordeaux, France

  • CHU Reims

    Reims, France

  • CHU Strasbourg

    Strasbourg, France

  • CHU de Grenoble

    Grenoble, France

  • CHU de Toulouse - Hôpital des enfants

    Toulouse, France

  • Centre Léon Bérard

    Lyon, France

  • Centre Oscar Lambret

    Lille, France

  • Hopital Arnaud de Villeneuve

    Montpellier, France

  • IUCT-O

    Toulouse, France