Experimental IV drug shows promise for tough childhood cancer

NCT ID NCT00646230

Completed Disease control Sponsor: New Approaches to Neuroblastoma Therapy Consortium Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested an intravenous form of the drug fenretinide in 17 children whose neuroblastoma had come back or didn't respond to standard treatments. The main goals were to find the safest dose and understand side effects. Researchers also looked at how the drug moved through the body and whether it could shrink tumors.

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Conditions

The condition(s) this trial relates to.

neuroblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROBLASTOMA

Contacts and locations

Locations

AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus

Atlanta, Georgia, 30322, United States
C.S. Mott Children's Hospital at University of Michigan Medical Center

Ann Arbor, Michigan, 48109-0286, United States
Children's Hospital Boston

Boston, Massachusetts, 02115, United States
Children's Hospital and Regional Medical Center - Seattle

Seattle, Washington, 98105, United States
Childrens Hospital Los Angeles

Los Angeles, California, 90027-0700, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229-3039, United States
Cook Children's Medical Center - Fort Worth

Fort Worth, Texas, 76104, United States
Hospital for Sick Children

Toronto, Ontario, M5G 1X8, Canada
Lucile Packard Children's Hospital at Stanford University Medical Center

Palo Alto, California, 94304, United States
Morgan Stanley Children's Hospital of New York-Presbyterian

New York, New York, 10032, United States
Texas Children's Cancer Center and Hematology Service at Texas Children's Hospital

Houston, Texas, 77030-2399, United States
UCSF Helen Diller Family Comprehensive Cancer Center

San Francisco, California, 94115, United States
University of Chicago Comer Children's Hospital

Chicago, Illinois, 60637, United States

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