New combo therapy targets tough childhood cancer
NCT ID NCT00509353
First seen Apr 19, 2026 · Last updated May 25, 2026 · Updated 8 times
Summary
This early-phase study tested a new treatment for children with high-risk neuroblastoma that did not respond to standard therapy or came back. The approach combines a radioactive drug (131I-MIBG) that targets tumor cells with two chemotherapy drugs (irinotecan and vincristine). The main goal was to find the safest dose of the radioactive drug when used in this combination, and to check for side effects. The study involved 26 children and aimed to see if the treatment could shrink tumors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus
Atlanta, Georgia, 30322, United States
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C.S. Mott Children's Hospital at University of Michigan Medical Center
Ann Arbor, Michigan, 48109-0286, United States
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Children's Hospital Boston
Boston, Massachusetts, 02115, United States
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Children's Hospital and Regional Medical Center - Seattle
Seattle, Washington, 98105, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104-4318, United States
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Childrens Hospital Los Angeles
Los Angeles, California, 90027-0700, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229-3039, United States
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Cook Children's Medical Center - Fort Worth
Fort Worth, Texas, 76104, United States
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Lucile Packard Children's Hospital at Stanford University Medical Center
Palo Alto, California, 94304, United States
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UCSF Helen Diller Family Comprehensive Cancer Center
San Francisco, California, 94115, United States
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University of Chicago Comer Children's Hospital
Chicago, Illinois, 60637, United States
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University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
Madison, Wisconsin, 53792-6164, United States
Conditions
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