New vaccine aims to train immune system to attack childhood cancer
NCT ID NCT00911560
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests a vaccine designed to help the immune system recognize and attack neuroblastoma, a type of childhood cancer. The vaccine contains two antigens found on neuroblastoma cells, plus an adjuvant to boost the immune response. Participants also take an oral supplement called β-glucan, which may help white blood cells kill cancer. The study includes children with high-risk neuroblastoma who have completed initial treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bivalent vaccine (GD2L and GD3L antigens linked to KLH) with OPT-821 adjuvant and oral β-glucan
What this could lead to
If successful, this vaccine could help the immune system target and kill neuroblastoma cells, potentially improving long-term control of the disease.
What could go wrong
This is an early-phase trial (phase I/II) with a small number of participants. The vaccine may not produce a strong enough immune response, or side effects could limit its use.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States