Double-Dose radiation attack shows promise for stubborn childhood cancer

NCT ID NCT00083135

Completed Disease control Sponsor: New Approaches to Neuroblastoma Therapy Consortium Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested a new approach for children with neuroblastoma that did not respond to standard treatments. It used two rapid infusions of a radioactive drug (I-MIBG) to target cancer cells, followed by a stem cell transplant to restore healthy blood cells. The goal was to find the safest dose and see if this method could control the disease.

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Conditions

The condition(s) this trial relates to.

neuroblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROBLASTOMA

Contacts and locations

Locations

Children's Hospital Boston

Boston, Massachusetts, 02115, United States
Children's Hospital Los Angeles

Los Angeles, California, 90027-0700, United States
Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229-3039, United States
Indiana University Cancer Center

Indianapolis, Indiana, 46202-5289, United States
UCSF Comprehensive Cancer Center

San Francisco, California, 94143, United States
University of Wisconsin Comprehensive Cancer Center

Madison, Wisconsin, 53792-6164, United States

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