NEUROBLASTOMA
Clinical trials for NEUROBLASTOMA explained in plain language.
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New hope for kids with resistant cancers: targeted drug enters trial
Disease control Not yet recruitingThis study tests a drug called ifinatamab deruxtecan (I-DXd) in children with solid tumors that have returned or not responded to treatment. The drug is an antibody-drug conjugate that targets cancer cells directly. The trial aims to check safety and see if tumors shrink in about…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New cell therapy aims to supercharge Kids' immune cells after transplant
Disease control Not yet recruitingThis early-phase trial tests a new cell therapy called ThINKK in 12 children aged 2–12 who have had a stem cell transplant for leukemia or neuroblastoma. The therapy is designed to boost the body's natural killer (NK) cells to better fight cancer. The main goals are to check if t…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Michel Duval • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New hope for kids with tough cancers: drug combo trial launches
Disease control Not yet recruitingThis study tests a combination of chemotherapy drugs (liposomal irinotecan, vincristine, and temozolomide) with or without an additional drug (anlotinib) in children aged 3-18 whose solid tumors have returned or not responded to treatment. The goal is to see if this combination c…
Matched conditions: NEUROBLASTOMA
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New CAR t cell therapy targets tough childhood cancers in early trial
Disease control Not yet recruitingThis early-phase study tests whether a new cell therapy called B7-H3 CAR T cells is safe and can help children and young adults whose solid tumors have returned or stopped responding to standard treatments. About 40 participants will receive their own immune cells that have been …
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Robbie Majzner • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Hope for kids with tough cancer: new combo trial launches
Disease control Not yet recruitingThis phase 2 trial tests three different combinations of a radioactive drug (131I-MIBG) with other medicines (vorinostat and/or dinutuximab) in children and young adults with relapsed or refractory neuroblastoma. About 118 participants will be randomly assigned to one of three tr…
Matched conditions: NEUROBLASTOMA
Phase: PHASE2 • Sponsor: New Approaches to Neuroblastoma Therapy Consortium • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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New scan could spot childhood cancer faster
Diagnosis Not yet recruitingThis study compares a new type of PET/CT scan using 18F-MFBG to the current standard scan (123I-MIBG) in 30 children with relapsed or refractory neuroblastoma. The goal is to see if the new scan works as well or better for detecting tumors. If it does, it could offer a quicker an…
Matched conditions: NEUROBLASTOMA
Phase: PHASE2 • Sponsor: Institut Curie • Aim: Diagnosis
Last updated Jun 26, 2026 13:16 UTC
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Light therapy may shield kids with cancer from chemo mouth sores
Prevention Not yet recruitingThis study tests whether light therapy (photobiomodulation) can prevent mouth sores in children receiving chemotherapy. Fifty children aged 0-30 will receive daily light treatments during hospital stays and at home. Researchers will check if the therapy is easy to use and accepta…
Matched conditions: NEUROBLASTOMA
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Prevention
Last updated Jun 27, 2026 14:01 UTC
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Can a simple scan save kids from paralysis during tumor surgery?
Knowledge-focused Not yet recruitingThis study looks back at medical records of 150 children who had surgery for neuroblastic tumors in the lower chest. Some had a special X-ray (arteriography) before surgery to map a key spinal artery, while others did not. Researchers want to see if the imaging helps prevent spin…
Matched conditions: NEUROBLASTOMA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:45 UTC