NEUROBLASTOMA
Clinical trials for NEUROBLASTOMA explained in plain language.
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New hope for kids with tough-to-treat nerve cancer: three-drug combo tested
Disease control Not yet recruitingThis study tests three different combinations of a radioactive drug (131I-MIBG) with other medicines (vorinostat and/or dinutuximab) in children and young adults with neuroblastoma that has come back or not responded to treatment. About 118 participants will be randomly assigned …
Matched conditions: NEUROBLASTOMA
Phase: PHASE2 • Sponsor: New Approaches to Neuroblastoma Therapy Consortium • Aim: Disease control
Last updated May 17, 2026 02:02 UTC
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Could engineered immune cells tackle childhood cancers that Won't quit?
Disease control Not yet recruitingThis early-stage study tests a new treatment called B7-H3 CAR T cells in up to 40 children and young adults whose solid tumors (like neuroblastoma) have come back or stopped responding to standard care. The therapy uses the patient's own immune cells, modified in a lab to better …
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Robbie Majzner • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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New immune booster aims to stop childhood cancer return after transplant
Disease control Not yet recruitingThis early-phase trial tests a new therapy called ThINKK in 12 children aged 2–12 who have had a stem cell transplant for leukemia or neuroblastoma. The therapy uses special immune cells to help the body's natural killer cells fight any remaining cancer cells. The main goal is to…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Michel Duval • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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New scan may improve detection of childhood cancer
Diagnosis Not yet recruitingThis study tests a new imaging method (18F-MFBG PET/CT) against the current standard scan (123I-MIBG) in 30 children with relapsed or refractory neuroblastoma. The goal is to see if the new scan is as good or better at finding tumors. Participants will receive both scans within a…
Matched conditions: NEUROBLASTOMA
Phase: PHASE2 • Sponsor: Institut Curie • Aim: Diagnosis
Last updated May 17, 2026 02:00 UTC
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Spinal cord safety in Children's chest tumor surgery: is Pre-Op imaging worth it?
Knowledge-focused Not yet recruitingThis study looks at whether doing a special X-ray (arteriography) before surgery to find a key spinal cord artery can prevent nerve damage in children with chest-area neuroblastic tumors. Researchers will review records of 150 children treated in France between 2005 and 2024. The…
Matched conditions: NEUROBLASTOMA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 17, 2026 02:03 UTC