New cell therapy aims to supercharge Kids' immune cells after transplant

NCT ID NCT07518654

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tests a new cell therapy called ThINKK in 12 children aged 2โ€“12 who have had a stem cell transplant for leukemia or neuroblastoma. The therapy is designed to boost the body's natural killer (NK) cells to better fight cancer. The main goals are to check if the treatment is safe and feasible, and to see how the immune system responds.

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Conditions

The condition(s) this trial relates to.

acute leukemia acute lymphoblastic leukemia acute myeloid leukemia childhood leukemia leukemia Neoplasm Metastasis neuroblastoma Paroxysmal nonkinesigenic dyskinesia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Sainte-Justine

    Montreal, Quebec, H3T1C5, Canada

  • The Hospital for Sick Children

    Toronto, Ontario, M5G1E8, Canada

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