HEALTHY VOLUNTEERS

This is an early-stage study to test the safety and immune response of a new vaccine candidate, VXB-241. The goal is to see if it can help prevent serious lung infections caused by two common viruses: Respiratory Syncytial Virus (RSV) and human metapneumovirus (HMPV). The study w…

This study is testing a new vaccine designed to protect infants and toddlers from 21 strains of pneumococcal bacteria, which can cause serious infections like pneumonia and meningitis. It will compare the new vaccine's safety and ability to trigger an immune response to an alread…

This study is testing a new mRNA vaccine designed to protect against a specific type of bird flu (H5) that could cause a future pandemic. Researchers want to see if the vaccine is safe and if it triggers a good immune response in healthy adults. The study will test three differen…

This study is testing a new vaccine designed to protect against five major types of meningococcal disease (A, B, C, W, Y) in children. It involves 750 healthy infants, toddlers, and children up to 9 years old. The main goals are to see how well the new vaccine triggers a protecti…

This is the first human study of an experimental drug called KK4277 for lupus. Researchers are testing the safety and side effects of single and multiple doses in healthy volunteers and people with different types of lupus. The study will also measure how much of the drug gets in…

This early-stage study is testing different types of black raspberry candy to see which version best delivers the berry's healthy compounds to the body. Healthy volunteers try candies that release the berry's ingredients at different speeds to find the most effective formula. The…

This research study aims to understand how analyzing people's genes (genome sequencing) can help us learn about heart disease and other health conditions. Researchers enrolled about 1,665 participants, including both healthy volunteers and people with heart disease, to collect bl…

This study aims to understand how a non-invasive brain stimulation technique called TMS affects decision-making, particularly in people with opioid use disorder. Researchers will compare 60 participants—some with opioid use disorder and some healthy volunteers—using brain scans a…

This study aims to test a new digital inhaler device in healthy volunteers. The device records breathing patterns and is designed to deliver medicine precisely to the lungs. Researchers will use a safe, traceable substance to see where it goes in the lungs and how the body proces…

This study aims to see if two different injection devices deliver the same amount of an investigational drug, amlitelimab, into the body. It will involve 212 healthy adult volunteers who will receive a single injection. Researchers will measure drug levels in the blood, check for…

This is an early, small study to understand how the body absorbs and processes a new tablet drug called ABBV-722. It involves 11 healthy volunteers and tests whether taking the drug with or without food changes how much of it gets into the bloodstream. The main goal is to gather …

This is the first study to test a new drug called JADE101 in people. It aims to check the safety and see how the body processes the drug in 32 healthy volunteers. Participants receive a single injection, and results will help plan future studies.

This is the very first study testing a new drug called ORKA-002 in humans. It aims to check if the drug is safe and to see how the body processes it after a single injection. The study involves about 24 healthy volunteers who will receive either the drug or a placebo. The main go…

This early-stage study aims to understand how two gout medications, epaminurad and C2406, interact when taken together. It will involve 18 healthy adults to measure the levels of each drug in the body and check for safety. The goal is to gather basic information to guide future r…

This study aimed to understand how smoking and vaping cause DNA damage in mouth cells, which might lead to cancer. Researchers planned to compare damage levels in people who continued using these products, those who tried to quit, and non-users. The goal was to identify which typ…

This study aims to understand what causes pulmonary fibrosis, a serious lung-scarring disease. Researchers will collect and analyze blood and tissue samples from about 315 people, including patients with fibrosis, their relatives, and healthy volunteers. The goal is to learn more…

This study aims to see if a new single pill containing three diabetes medicines works the same way in the body as taking the three medicines as separate pills. It involves healthy adult volunteers who will take both the single combination pill and the separate pills at different …

This study aims to understand how a gentle, non-invasive electrical stimulation applied to the ear affects brain activity and the body's automatic nervous system. Researchers are testing this on 44 healthy volunteers to see how it changes brain wave patterns and heart rate variab…

This is a very early safety study testing a new drug called budoprutug in healthy volunteers. Researchers will give single injections to 38 healthy adults to see how safe the drug is and how the body processes it. The main goal is to understand side effects and determine appropri…

This early-stage study is investigating whether sirolimus, an FDA-approved medication, can improve blood flow to the brain in healthy adults who carry a genetic risk for Alzheimer's disease. Researchers are using MRI scans to measure changes in brain blood flow and, in a second p…

This study aims to gather basic information about how a special imaging agent, called [13C]pyruvate, behaves in the bodies of healthy volunteers during an MRI scan. Researchers want to see how this agent is distributed and used for energy in different organs to create a normal re…

This study was designed to understand how different drugs and drug combinations affect people's mood, pain tolerance, and mental performance. It planned to enroll healthy volunteers to take study drugs and complete tasks measuring their feelings, thinking, and pain response. The …

This study is testing a new version of a common eye imaging machine, called Optical Coherence Tomography (OCT), on healthy volunteers. The goal is to check the image quality and test new software to make the scanner faster and clearer. Researchers hope this improved technology wi…

This study aims to understand how gut bacteria influence how well a common cholesterol medication works, and how that medication changes gut bacteria. Researchers will give healthy volunteers either the medication or a placebo for 8 weeks and track changes in their gut bacteria a…

This study aims to understand what happens in the brain and body during a psychedelic experience. Researchers will give psilocybin (the active compound in 'magic mushrooms') to 12 healthy volunteers and scan their brains using MRI machines while they are under its effects. The go…

This study aims to understand the dream-like experiences people have while under light anesthesia. Healthy adult volunteers will receive two different types of sedation while researchers measure their brain waves and interview them about their experiences. The goal is to learn ho…

This early-stage study aims to understand how a new combination pill containing two cancer drugs is absorbed by the body compared to taking the drugs separately. It will also test whether eating food changes how the pill works. The study involves 24 healthy adult volunteers to ga…

This study is creating a large community health registry and sample bank in Cabarrus County and Kannapolis, North Carolina. It aims to enroll 50,000 local residents to provide their health information and biological samples. The collected data will be used as a resource for futur…