Healthy volunteers test dupilumab shot with enzyme helper

NCT ID NCT07646548

First seen Jun 26, 2026 · Last updated Jul 22, 2026 · Updated 3 times

Summary

This early-stage study is testing whether adding an enzyme called berahyaluronidase alfa changes how the body processes dupilumab (Dupixent), a drug used for conditions like eczema and asthma. Forty healthy adults will receive a single injection of dupilumab either with or without the enzyme. The goal is simply to compare the drug levels and side effects between the two groups — there is no treatment benefit for participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Dupilumab (Dupixent) with or without berahyaluronidase alfa

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Pharmacology of Miami- Site Number : 8400001

    Hialeah, Florida, 33014, United States

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