New quadrivalent meningitis vaccine shows promise in large pediatric trial

NCT ID NCT07135986

First seen Oct 31, 2025 · Last updated Jun 23, 2026 · Updated 39 times

Summary

This Phase 3 study is testing an investigational meningococcal conjugate vaccine (MenACYW) in over 1,600 healthy children and adolescents aged 2 to 17 in China. The vaccine aims to protect against four types of meningococcal bacteria that can cause serious infections like meningitis. Researchers are comparing the new vaccine's immune response and safety to currently licensed meningococcal vaccines in China.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEALTHY VOLUNTEERS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Investigational Site Number : 1561000

    Nanning, Guangxi, 530028, China

  • Investigational Site Number : 1561001

    Jingxi, 533899, China

  • Investigational Site Number : 1561002

    Tengzhou, 543399, China

  • Investigational Site Number : 1561003

    Liuzhou, 545100, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MenACYW conjugate vaccine (MenQuadfi)

What this could lead to

If successful, this vaccine could provide broader protection against four types of meningococcal bacteria with a single shot, potentially simplifying vaccination schedules for children and teens.

What could go wrong

This is a Phase 3 trial, but it is still testing the vaccine's immune response and safety. The vaccine may not prove superior to existing vaccines, and rare side effects could emerge in larger populations.

Conditions

The condition(s) this trial relates to.

meningococcal infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.