New quadrivalent meningitis vaccine shows promise in large pediatric trial

NCT ID NCT07135986

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 study is testing an investigational meningococcal conjugate vaccine (MenACYW) in over 1,600 healthy children and adolescents aged 2 to 17 in China. The vaccine aims to protect against four types of meningococcal bacteria that can cause serious infections like meningitis. Researchers are comparing the new vaccine's immune response and safety to currently licensed meningococcal vaccines in China.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
MenACYW conjugate vaccine (MenQuadfi)
What this could lead to
If successful, this vaccine could provide broader protection against four types of meningococcal bacteria with a single shot, potentially simplifying vaccination schedules for children and teens.
What could go wrong
This is a Phase 3 trial, but it is still testing the vaccine's immune response and safety. The vaccine may not prove superior to existing vaccines, and rare side effects could emerge in larger populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number : 1561000

    Nanning, Guangxi, 530028, China

  • Investigational Site Number : 1561001

    Jingxi, 533899, China

  • Investigational Site Number : 1561002

    Tengzhou, 543399, China

  • Investigational Site Number : 1561003

    Liuzhou, 545100, China

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