HEALTHY VOLUNTEERS

This study tested a new meningococcal B vaccine in 576 healthy people, from infants to adults. The goal was to check its safety and how well it triggers the immune system, comparing it to existing vaccines. The trial was terminated early, so final results may be limited.

This early-stage study tested a new drug called ASP5502 in healthy adults and people with primary Sjögren's syndrome, a condition where the immune system attacks moisture-producing glands. The main goal was to check safety and how well the drug is tolerated. The study was stopped…

This study tested an experimental drug, PF-07258669, to help older adults (60-90 years) who are at risk of malnutrition or losing weight without trying. The goal was to see if the drug is safe and how it affects the body. The trial was stopped early after enrolling only 7 partici…

This study aimed to discover substances in blood and urine that could signal kidney damage earlier than current tests. Researchers compared samples from healthy volunteers, people with low fluid levels, those at high risk for kidney failure, and patients with acute kidney failure…

This study tested two new liquid versions of the drug maribavir to see how well they are absorbed and how they taste compared to the current tablet. It involved 20 healthy adults aged 18-50. The study was terminated early, so results are limited.

This early-stage study tested a new drug called iCP-NI in 24 healthy adults to check its safety and how the body processes it. Participants received either the drug or a placebo through an IV. The study was terminated early, and no treatment for any disease was being tested.

This study surveyed teens aged 13-18 and their parents to understand attitudes toward vaping, mental health, and social influences. Participants answered anonymous questions online about vaping habits, drug use, mood, and gaming. No treatment was given; the goal was to gather inf…

This study looked at whether a mindfulness training program can change brain connections in teenagers who vape tobacco. Researchers used brain scans to measure changes before and after training, and asked participants about their vaping habits. The goal was to see if mindfulness …

This early-phase study tested the safety of a new drug called AMG 378 in 48 healthy adults aged 18 to 55. Participants received either the drug or a placebo to check for side effects and how the drug moves through the body. The study was terminated early, and no treatment or heal…

This study looked at how healthy adults react to breathing air with less oxygen for several days. Researchers measured oxygen levels in the blood, red blood cell production, and lung pressure to understand the body's response. The goal was to learn about safety and basic body cha…

This early-stage study tested a new radioactive drug called [11C]MC1 to see if it could help PET scans show inflammation in the body. Researchers studied healthy volunteers and people with rheumatoid arthritis or inflammatory muscle disease. The study was stopped early, but the g…

This study tested new ways to take detailed pictures of the lungs using MRI with special inhaled gases. Healthy volunteers aged 6 to 75 had lung scans to help improve the imaging technology. The goal was to develop better hardware and software, not to treat any disease.

This small study tested whether a single session of non-invasive brain stimulation (alpha-tACS) could change brain activity and help people be less stuck in their habits. Seven healthy adults, including some with risky drinking histories, completed tasks while receiving real or f…