Breathing in a new way to see lungs: MRI with tracer gases
NCT ID NCT04726618
First seen Jun 26, 2026 ยท Last updated Jun 26, 2026
Summary
This study tested two special gases (hyperpolarized xenon and perfluoropropane) that people inhale to make their lungs show up better on an MRI. The goal was to develop better imaging methods and hardware to get clearer pictures of lung function. The study involved 24 healthy volunteers aged 6 to 75 and focused on improving image quality and comparing the two gases.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Hyperpolarized 129-xenon gas and perfluoropropane gas
- What this could lead to
- If successful, this could lead to better, safer ways to image lung function without radiation, helping diagnose lung diseases more accurately.
- What could go wrong
- This was a small, early-stage study in healthy volunteers that was terminated, so results are limited. The techniques may not work as well in people with lung disease.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital for Sick Children
Toronto, Ontario, M5G 0A4, Canada
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