HEALTHY VOLUNTEERS

This study is checking how safe a high-dose flu vaccine called Efluelda is for adults aged 65 and older in South Korea. About 670 people will receive the vaccine and be watched for side effects over about a month. The goal is to see what reactions occur in everyday medical practi…

This early-phase study tests a new radioactive imaging agent called MeFAMP to see if it can safely and accurately detect brain tumors using PET scans. The study includes healthy volunteers and people with recurrent brain tumors or tumors that spread from other cancers. The goal i…

This study tests a new way to prevent obesity in teens and young adults (ages 18-25) who are at high risk due to family history and higher body weight. Participants will receive lifestyle coaching and possibly medication to help control weight gain. The goal is to stop unhealthy …

This study tests whether a single dose of (2R,6R)-HNK, a drug related to ketamine, can reduce short-term pain in healthy adults without the addictive risks of opioids. Up to 92 volunteers aged 18-60 will receive either the drug, a placebo, or no treatment, and undergo pain tests …

This early-stage study tests whether a new formulation of the antibiotic polymyxin B (VRP-034) causes less kidney injury than the current version. About 48 healthy adult men will receive single or multiple doses of either the new or standard drug. Researchers will measure kidney …

This early-stage study tests a new type of brain stimulation called high-density theta burst stimulation (hdTBS) in 35 healthy adults aged 22 to 60. The goal is to check if it is safe and to see how it affects brain activity compared to standard stimulation. Participants will hav…

This study will test three different portable inhaler devices in 10 healthy adults. Each person will try all three devices in random order. The goal is to see how well the devices control airflow, record breaths, and feel comfortable to use. No medicine is involved—only a salt-ba…

This early-stage study looks at whether the hormone progesterone affects how muscles build protein after resistance exercise. Twenty healthy women aged 18-30 will take either progesterone or a placebo, then do leg exercises. Researchers will measure muscle changes through biopsie…

This study looks at whether doing sit-to-stand exercises with a blood flow restriction cuff on the legs can improve back muscle endurance and balance better than the same exercises without the cuff. The study involves 70 healthy adults aged 20-25 who will exercise twice a week fo…

This study is an early-stage trial to check the safety of a new drug called VV913 in healthy Chinese men aged 18 to 45. It involves giving multiple doses of the drug or a placebo to see how the body handles it and if any side effects occur. The goal is to gather safety and drug-l…

This early-stage study tests a single injection of a new drug called KL0011034 in 76 healthy Chinese volunteers aged 18-45. The main goal is to check for side effects and measure how the drug moves through the body. Participants are randomly assigned to receive the drug, a placeb…

This study tests a new technology called focused ultrasound, which uses sound waves to gently stimulate specific brain areas. Researchers will apply this to the vision and hearing centers of 20 healthy adults to see how it affects perception. The goal is to find the best settings…

This study looks at whether the shape of a breathing mask changes how healthy people breathe while using a machine that helps with breathing (non-invasive ventilation). Ten healthy adults will try four different masks and have their breathing measured. The goal is to learn which …

This study looks at how the length of heart rate recording affects results during a mild nerve stimulation in healthy adults. Forty volunteers will receive both real and sham stimulation in random order. The goal is to find the most reliable recording duration for detecting chang…

This early-stage study tests two different liquid forms of metformin against the usual tablet in 24 healthy adults. Researchers will measure blood sugar levels over a few hours to see how the liquid versions compare. The goal is to gather information, not to treat any disease.

This early-stage study tests the safety of a single oral dose of ZE74-0282 in 40 healthy adults aged 18 to 55. Researchers will monitor for side effects and measure how the drug moves through the body. No treatment is given; the goal is to gather safety data before testing in pat…

This study looks at whether a single dose of nicotinamide riboside (NR), a common supplement, can change how healthy adults sleep. Twenty people with mild sleep troubles will have their sleep measured in a lab after taking NR or a placebo. The goal is to see if NR has any immedia…

This study looks at whether Kinesio Taping can immediately improve hand and arm performance in healthy adults. 36 participants will be randomly assigned to receive real Kinesio Taping, a sham (fake) taping, or no taping at all. The goal is to see if any improvements come from the…

This early-stage study tests the safety of a new drug called migaldendranib in 36 healthy volunteers. Participants receive weekly injections, and researchers monitor for side effects and how the drug moves through the body. The goal is to gather safety information, not to treat a…

This study looks at how different vibration frequencies from a smartphone app affect hand strength, touch sensitivity, pain threshold, and reaction time in healthy young adults. Twenty participants will test three vibration levels on their dominant hand in random order. The goal …

This study looks at whether a supplement called TRPTI (oleoylethanolamide) can lower a substance in the blood linked to insulin resistance and improve metabolic health. Researchers will compare TRPTI to a placebo in 90 healthy adults over 8 weeks. Participants take capsules daily…

This study tests five different frequencies of vagus nerve stimulation (including a sham/placebo) in 36 healthy adults aged 18-30. The goal is to see which frequency best changes heart rate variability, blood pressure, and breathing rate. Participants will receive all frequencies…

This study aims to see if a simple, markerless motion capture system using only four cameras can accurately measure how children walk. Researchers will compare this new method to traditional lab-based systems in 125 healthy volunteers aged 6 to 17. If successful, this approach co…

This early-stage study looks at how a high-fat meal and two common drugs (rifampicin and itraconazole) affect the levels of the experimental drug CS0159 in the body. Thirty-two healthy adults aged 18 to 45 will take CS0159 under different conditions to measure drug concentrations…

This early-stage study tests the safety and tolerability of a new drug called KMY Tablets in 120 healthy volunteers aged 18 to 45. The trial will look at how the body handles single and multiple doses, and whether food affects drug levels. No treatment benefit is expected; the go…

This early-stage study tests the safety of a new drug called HS-20152 in 32 healthy adults aged 18 to 64. Participants receive a single dose of the drug or a placebo, and researchers monitor for side effects and how the drug moves through the body. The goal is to gather initial s…

This study aims to improve how a device recognizes hand gestures by using a new computer algorithm. Ten healthy, right-handed adults will wear a muscle-signal sensor on their forearm and perform gestures. The researchers will compare the new algorithm's accuracy to standard metho…

This study looks at how a targeted nerve block near the wrist affects blood flow in healthy adults. Researchers will measure changes in finger pulse and hand temperature before and after the block, using cold water tests to trigger natural responses. The goal is to better underst…

This study looks at how stimulating a nerve in the ear for different amounts of time (5, 10, or 15 minutes) changes heart rate, blood pressure, and breathing in healthy adults. 44 volunteers will receive either real or fake stimulation. The goal is to understand if longer stimula…

This early-stage study aims to see if liquid metformin causes fewer stomach side effects than the standard tablet form. Twenty-four healthy adults will try single doses of two different liquid strengths and one tablet, then be monitored for side effects. The study does not offer …

This study compares how people with idiopathic environmental intolerance (IEI) and healthy volunteers process information about their bodies and the environment. Researchers want to see if certain thinking patterns or biases explain why IEI patients feel sick from everyday exposu…

This study checks if two drugs, IN-M00007 and IN-R00007, are absorbed and processed the same way in the body. It involves 60 healthy adults aged 19 to 59. Each person takes a single dose of both drugs at different times, and researchers measure drug levels in the blood to compare…

This early-stage study tests how the body handles a single dose of the experimental drug BMS-986435 in 24 adults with normal liver function or mild-to-moderate liver impairment. The goal is to measure drug levels and safety, not to treat any disease. Participants must have health…

This early-stage study looks at how a new liquid form of sildenafil (the drug in Viagra®) works after drinking alcohol. Twenty-four healthy adults will take the medication under controlled conditions. Researchers will measure drug levels in the blood and how quickly participants …

This early-stage study tests an experimental oral drug called ISM4808 in 86 healthy adults in China. The main goal is to check if the drug is safe and how the body processes it. Participants will receive either the drug or a placebo, and researchers will monitor for side effects.…

This study tests whether real-time fMRI can help healthy volunteers change how they perceive social information, like seeing interactions as positive or negative. Ten participants will undergo six MRI sessions to learn to control brain activity linked to social perception. The go…

This study looks at how brief periods of low oxygen (like those in sleep apnea) change the body's breathing control system. Researchers will measure breathing stability in 40 healthy adults before and after 6 hours in a low-oxygen chamber. The goal is to understand if these oxyge…

This study looks at how different phases of the menstrual cycle relate to muscle strength and physical performance in active women aged 18-35. Participants track their cycle with a phone app and attend 3 lab visits for strength tests and body measurements. The goal is to better u…

This study looks at how different frequencies of a mild ear nerve stimulation (taVNS) change heart rate, blood pressure, and breathing in healthy adults aged 18 to 40. Each person will try five different stimulation settings (including a sham) in separate sessions. The goal is to…

This early-stage study tests whether a single shot of GenSci161 is safe and how the body processes it. About 44 healthy adults aged 18 to 45 will take part. No treatment is given—this is purely to gather safety and drug-level information.