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Sound waves aim to unlock Brain's secrets in healthy volunteers

NCT ID NCT07508722

Knowledge-focused Sponsor: Massachusetts Institute of Technology Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study explores how focused ultrasound can change brain activity in healthy adults. Researchers will send sound waves through the skull to the visual and hearing parts of the brain to see what people perceive. The goal is to find the best settings for future treatments of conditions like chronic pain and depression. Twenty healthy volunteers aged 21-55 will participate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

The inclusion criteria for this study are as follows: 1. Healthy male and female adults aged 21-55. 2. No contraindications to magnetic resonance imaging (MRI) scans, such as claustrophobia. The exclusion criteria for this study are as follows: 1. History of major medical, neurological (including peripheral nerve disease) or psychiatric illness. 2. History of vsacular conditions, predisposition to hemorrhage, or blood thinner medications 3. History of head trauma with loss of consciousness. 4. Use of sedatives, analgesics and agents that affect brain function. 5. Contraindications for exposure to the high magnetic field of MRI imaging 6. History of skin irritation from acoustic coupling materials such as a water-based gel and polyvinyl alcohol (PVA; a common household plastic bag material). 7. Vulnerable subpopulations (pregnant women, children, institutionalized individuals). 8. Use of excessive alcohol (e.g., no more than one can of beer or glass of wine) or strenuous exercise (e.g., no more than daily routine) on the day of the visit

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteers No condition, basic science

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Massachusetts Institute of Technology - McGovern Institute for Brain Research

    Cambridge, Massachusetts, 02139, United States

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