New brain zapping technique tested for safety in healthy volunteers
NCT ID NCT06868914
First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 4 times
Summary
This early-stage study tests a new form of transcranial magnetic stimulation (TMS) called high-density theta burst stimulation (hdTBS) in 35 healthy adults aged 22 to 60. The goal is to check if hdTBS is safe and to compare its effects on the brain to standard TMS. Participants will receive both real and sham stimulation over several visits while researchers monitor side effects and brain activity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial magnetic stimulation (TMS) using high-density theta burst stimulation (hdTBS)
What this could lead to
If successful, this could pave the way for testing hdTBS as a potential treatment for conditions like depression or addiction.
What could go wrong
This is an early Phase 1 safety study in only 35 healthy volunteers, so results may not apply to patients. The new stimulation method may not work better than existing TMS.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institute on Drug Abuse
Baltimore, Maryland, 21224, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••