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New 5-in-1 meningitis shot could protect kids from five strains at once

NCT ID NCT06647407

Ongoing ⭐️ VACCINE ⭐️ Sponsor: Sanofi Pasteur, a Sanofi Company Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new pentavalent meningococcal vaccine (MenPenta) that aims to protect against five types of meningococcal bacteria (A, B, C, W, Y) in healthy children, toddlers, and infants. Researchers will compare it to existing licensed vaccines and check how well it works when given alone or with routine childhood shots. The trial involves 750 participants across three age groups and will monitor immune response and side effects for up to 19 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Pentavalent Meningococcal ABCYW vaccine (MenPenta)
What this could lead to
If successful, this could lead to a single vaccine that protects against five major types of meningococcal disease, simplifying childhood immunization schedules.
What could go wrong
This is an early-phase study (phase 1/2) with only 750 participants, so results may not confirm broad effectiveness or safety. The vaccine may not produce a strong enough immune response in all age groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

meningococcal infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY VOLUNTEERS MENINGOCOCCAL IMMUNIZATION

Contacts and locations

Locations

  • Hospital das Clínicas da Universidade Federal de Minas Gerais- Site Number : 0760001

    Belo Horizonte, Minas Gerais, 30130-100, Brazil

  • Investigational Site Number : 2030003

    Jindřichův Hradec, 377 01, Czechia

  • Investigational Site Number : 2030004

    Ostrava, 700 30, Czechia

  • Investigational Site Number : 2030007

    Pilsen, 301 00, Czechia

  • Investigational Site Number : 2030008

    Prague, 180 00, Czechia

  • Investigational Site Number : 2030009

    Prague, 180 00, Czechia

  • Investigational Site Number : 2080002

    Hvidovre, 2650, Denmark

  • Investigational Site Number : 2080003

    Odense, 5000, Denmark

  • Investigational Site Number : 2460001

    Helsinki, 00100, Finland

  • Investigational Site Number : 2460002

    Seinäjoki, 60100, Finland

  • Investigational Site Number : 2460004

    Oulu, 90220, Finland

  • Investigational Site Number : 2460005

    Jarvenpaa, 04400, Finland

  • Investigational Site Number : 2460006

    Espoo, 02230, Finland

  • Investigational Site Number : 2460007

    Tampere, 33100, Finland

  • Investigational Site Number : 2460008

    Helsinki, 00290, Finland

  • Investigational Site Number : 2760003

    Wolfsburg, 38448, Germany

  • Investigational Site Number : 2760004

    Schönau am Königssee, 83471, Germany

  • Investigational Site Number : 2760005

    Krefeld, 47799, Germany

  • Investigational Site Number : 2760006

    Hürth, 50354, Germany

  • Investigational Site Number : 2760007

    Hürth, 50354, Germany

  • Investigational Site Number : 2760008

    Herxheim, 76863, Germany

  • Investigational Site Number : 2760009

    Mönchengladbach, 41236, Germany

  • Investigational Site Number : 3400001

    San Pedro Sula, Honduras

  • Investigational Site Number : 3400002

    Tegucigalpa, 11101, Honduras

  • Investigational Site Number : 3400003

    Tegucigalpa, 11101, Honduras

  • Investigational Site Number : 6160001

    Lodz, Lódzkie, 91-347, Poland

  • Investigational Site Number : 6160002

    Warsaw, Masovian Voivodeship, 02-793, Poland

  • Investigational Site Number : 6160003

    Warsaw, Masovian Voivodeship, 02-647, Poland

  • Investigational Site Number : 6160004

    Siemianowice Śląskie, Silesian Voivodeship, 41-103, Poland

  • Investigational Site Number : 6160005

    Trzebnica, Lower Silesian Voivodeship, 55-100, Poland

  • Investigational Site Number : 6160006

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-090, Poland

  • Investigational Site Number : 7240004

    Madrid, 28938, Spain

  • Investigational Site Number : 7240007

    Seville, Sevilla, 41013, Spain

  • Investigational Site Number : 7240009

    Madrid, 28041, Spain

  • Investigational Site Number : 8260004

    Exeter, Devon, EX2 5DW, United Kingdom

  • Investigational Site Number : 8260007

    London, England, E1 1BB, United Kingdom

  • Investigational Site Number : 8260009

    London, England, SW17 0QT, United Kingdom

  • Investigational Site Number : 8260010

    Southampton, Hampshire, SO16 6YD, United Kingdom

  • Private Practice - Dr. Nelson Rosário- Site Number : 0760004

    Curitiba, Paraná, 80810-100, Brazil

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