New lupus drug KK4277 enters first human safety trials
NCT ID NCT05411016
First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 28 times
Summary
This early-stage study is testing a new drug called KK4277 to see if it is safe for people with lupus. The trial first gives a single dose to healthy men, then repeated doses to people with systemic or cutaneous lupus. The main goal is to check for side effects and measure how the drug moves through the body.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ajou University Hospital
Suwon, Gyeonggi-do, 16499, South Korea
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Fujita Health University Hospital
Kutsukake, Aichi-ken, 470-1192, Japan
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Fukushima Medical University Hospital
Fukushima, 960-1295, Japan
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Institute of Science Tokyo Hospital
Bunkyō-Ku, Tokyo, 113-8519, Japan
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Japan Community Health care Organization Chukyo Hospital
Minami, Aichi-ken, 457-8510, Japan
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Japan Institute for Health Security National Center for Global Health and Medicine
Shinjuku-Ku, Tokyo, 162-8655, Japan
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Juntendo University Nerima Hospital
Tokyo, 177-8521, Japan
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Juntendo University Urayasu Hospital
Urayasu, Chiba, 279-0021, Japan
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Kanazawa University Hospital
Kanazawa, Ishikawa-ken, 920-8641, Japan
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Keio University Hospital
Shinjuku-Ku, Tokyo, 160-8582, Japan
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Kitasato University Hospital
Minami, Kanagawa, 252-0375, Japan
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Kyusyu University Hospital
Higashi, Fukuoka, 812-8582, Japan
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Medical Co. LTA Sumida Hospital
Sumida-ku, Tokyo, 130-0004, Japan
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Nagasaki University Hospital
Nagasaki, 852-8501, Japan
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National University Corporation Tohoku University Tohoku University Hospital
Aoba, Miyagi, 980-8574, Japan
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Niigata University Medical & Dental Hospital
Chuo Ku, Niigata, 951-8520, Japan
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Saitama Medical University Hospital
Moriyama, Saitama, 350-0495, Japan
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Seoul National University Hospital
Seoul, 03080, South Korea
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Showa Medical University East Hospital
Shinagawa-Ku, Tokyo, 142-0054, Japan
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St. Luke's International Hospital
Chuo Ku, Tokyo, 104-8560, Japan
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University of the Ryukyus Hospital
Ginowan, Okinawa, 901-2725, Japan
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Wakayama Medical University Hospital
Wakayama, 641-8510, Japan
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Yokohama City University Medical Center
Minami, Kanagawa, 232-0024, Japan
Conditions
Explore the condition pages connected to this study.