COGNITIVE IMPAIRMENT

This study aims to see if advanced scans of the eyes and brain can help doctors better spot and treat a type of nerve and blood vessel damage linked to diabetes. Researchers will also test whether a traditional Chinese herbal medicine called Tangshen'an Granule is safe and effect…

This study aims to see if eating foods high in resistant starch can help slow down memory and thinking problems in adults who are at high genetic risk for cognitive decline and are overweight. 70 participants will be randomly assigned to eat either the special starch foods or reg…

This study is testing whether a simple, non-invasive arm cuff treatment can help improve or prevent memory loss in people with a specific brain blood vessel disease. Forty adults with mild memory problems will use the cuff or a fake version twice daily for 90 days. Researchers wi…

This study is testing if a non-invasive brain stimulation technique (rTMS) can improve 'cognitive flexibility'—the ability to switch between thoughts and tasks—in people with major depression. Researchers believe a specific weak connection in the brain causes this thinking proble…

This study is testing a new support package for older adults who have two or more long-term health problems, like high blood pressure, diabetes, or arthritis. The package includes digital tools, personalized guidance, and ongoing support to help manage their health. Researchers w…

This study tests a virtual coaching program called ViCCY designed to help caregivers of adults with heart failure and memory problems. Caregivers will receive 10 coaching sessions over 6 months to learn self-care strategies and reduce stress. The research aims to see if supportin…

This study aims to find out if cognitive rehabilitation delivered remotely via video calls (tele-rehabilitation) works as well as traditional in-person therapy for improving memory and thinking skills after a stroke. Researchers will randomly assign 32 stroke survivors to receive…

This study is testing if a handheld robot that provides gentle vibrations along with audio guidance can help older adults with memory concerns sleep better. It compares this robot-guided meditation to standard audio-only meditation apps. The goal is to see if the physical feedbac…

This study is testing whether a gentle, whole-body vibration therapy can help improve memory, balance, and quality of life for older adults with mild cognitive impairment. Participants will stand on a platform that vibrates slightly three times a week for 12 weeks. Researchers wi…

This study is testing a non-invasive brain stimulation technique to see if it can improve memory, attention, and other thinking skills in people with stable bipolar disorder. Researchers will use magnetic pulses targeted at a specific brain circuit while participants do computer-…

This study is testing whether aerobic exercise and a gentle, non-invasive brain stimulation technique (tDCS) can help improve memory, attention, and other thinking skills in people with schizophrenia that hasn't responded well to standard medications. 160 participants will be ran…

This study is testing whether giving home health aides extra training in dementia care helps reduce difficult behaviors in older adults with memory problems and improves their quality of life, as well as the well-being of their family caregivers. It will involve 60 pairs of patie…

This study aims to see if tracking eye movements can accurately detect impairment from THC, the main active ingredient in cannabis. Researchers will give different doses of THC or a placebo to 40 frequent and infrequent cannabis users and test their eye control and attention. The…

This study is testing the best way to research why some older adults experience confusion or memory problems after major surgery. Researchers will ask about 40 patients aged 70+ to do memory tests and give blood samples before and after their operation. The goal is to gather info…

This study aims to understand if a brief memory test given before hip replacement surgery can help predict which older patients might experience sudden confusion after their operation. Researchers will observe about 400 patients aged 65 and older across several hospitals in the C…

This study is testing a new, more detailed health check designed specifically for older adults being evaluated for a kidney transplant. Researchers want to see if adding this 45-60 minute check to the standard assessment is practical and acceptable for patients and doctors. The s…