Could an old antibiotic shield the brain in sickle cell disease?
NCT ID NCT05605366
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether minocycline, an antibiotic that reduces brain inflammation, can safely prevent or reverse memory and thinking problems in adults with sickle cell disease. About 30 participants will take either a low dose, high dose, or placebo for one year. Researchers will monitor side effects and check cognitive changes using standard thinking tests.
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