Could an old antibiotic shield the brain in sickle cell disease?

NCT ID NCT05605366

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether minocycline, an antibiotic that reduces brain inflammation, can safely prevent or reverse memory and thinking problems in adults with sickle cell disease. About 30 participants will take either a low dose, high dose, or placebo for one year. Researchers will monitor side effects and check cognitive changes using standard thinking tests.

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Conditions

The condition(s) this trial relates to.

Cognition Disorders cognitive disorder Cognitive Dysfunction Neuroinflammatory Diseases neuronitis sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

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    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

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