Brain training and new drug combo tested to fight memory loss in stroke risk patients
NCT ID NCT07605130
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a tablet-based brain training program and/or a powerful cholesterol-lowering drug (PCSK9 inhibitor) can improve thinking and memory in 420 adults aged 55-80 with narrowed brain arteries. Participants will be split into four groups, combining or not combining the training with standard or intensive cholesterol treatment. The main goal is to see if these approaches boost cognitive scores after 24 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Recaticimab (PCSK9 inhibitor) injection, plus statins and ezetimibe
- What this could lead to
- If successful, this could point toward a way to slow or improve cognitive decline in people with intracranial atherosclerosis.
- What could go wrong
- This is a Phase 4 trial with 420 participants, so results are not yet known. The cognitive training is intensive (30 min/day, 5 days/week), and the added drug may cause side effects like injection site reactions or muscle pain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Peking Union Medical College Hospital
Beijing, Beijing Municipality, 100730, China
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