Starch shield: could resistant starch slow memory loss?

NCT ID NCT07152483

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 31 times

Summary

This study tests whether eating foods high in resistant starch (a type of fiber) can slow down memory decline in people at high genetic risk for cognitive impairment. Seventy adults aged 40 and older with a high genetic risk score and mild memory issues will be randomly assigned to eat either high-resistant starch foods or regular starch foods for a period. Researchers will track changes in thinking skills, blood and gut markers, and brain scans to see if the diet helps protect the brain.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Second Affilated Hospital of Zhejiang University, School of Medicine

    Hangzhou, Zhejiang, 310009, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

resistant starch (dietary supplement)

What this could lead to

If it works, this could point toward a simple dietary change to help slow memory loss in people at high genetic risk.

What could go wrong

This is a small, early-stage study with only 70 participants. It is not yet recruiting, and results may not apply to everyone. Dietary changes can be hard to stick with.

Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.