OBESITY & OVERWEIGHT

This study looks at whether eating only during certain hours (early or late in the day) can help control blood sugar and improve heart health in people who are overweight and have normal blood sugar, prediabetes, or type 2 diabetes. Researchers will track 30 participants' glucose…

This study tests an injection called UBT251 in 180 adults who are overweight or obese and have chronic kidney disease. The goal is to see if it can reduce protein in the urine, a sign of kidney damage, over 24 weeks. Participants will receive either the drug or a placebo, and the…

This study looks at whether a daily grape powder drink can improve gut health and reduce inflammation in adults with obesity. Researchers will measure changes in gut bacteria, immune markers, and stress levels. The study involves 50 participants aged 30-45 with a BMI of 30-45. It…

This study tests a new drug called RN3161, alone and combined with tirzepatide (a known weight loss medication), in adults with overweight or obesity. The goal is to check safety, how the body processes the drug, and its effect on body weight. About 104 people will join this earl…

This study tests whether an upgraded smartphone app helps people follow their bariatric surgery plan better than the standard app. About 200 adults having weight-loss surgery will use either the regular or an enhanced version of the "Get Ready" app. Researchers will track weight …

This study looks at whether adding a GLP-1 appetite suppressant to behavioral therapy helps people with severe obesity and binge eating disorder. About 80 adults will be split into two groups: one gets the drug plus therapy, the other gets therapy alone. Researchers will track ch…

This study tests a mobile app called FoodTraining that trains people to better control their responses to food. It is for adults with obesity, binge-eating disorder, or bulimia who are already receiving standard treatment. Participants use the app for 4 weeks alongside their usua…

This study compares two methods (pressure support ventilation and T-piece) used to test if overweight ICU patients are ready to have their breathing tube removed. About 100 adults with a BMI of 25 or higher who have been on a ventilator for over 24 hours will be randomly assigned…

This study tests whether giving overweight teens free fruits and vegetables from a local farm for 8 weeks can help them eat more produce and improve their blood pressure and weight. About 50 teens aged 12-17 will get weekly produce and watch educational videos. Researchers will m…

This study looks at whether blocking the ghrelin (hunger) receptor can further reduce appetite in people with obesity who are already taking semaglutide. About 24 adults on a stable dose of semaglutide will receive either a natural blocker (LEAP2) or a placebo during two study vi…

This study looks at how taking multiple medications affects the health of elderly people with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will survey 2000 patients aged 65 and older in Shaanxi Province, China, over two years. The goal is to…