OBESITY & OVERWEIGHT

This study tests whether adding a weight-loss medication (a GLP-1 drug) to standard chemo-radiation before surgery helps rectal cancer patients with a high BMI. About 42 participants will either get the drug plus standard treatment or standard treatment alone. Researchers will me…

This study tests a new injection called IN-B00009 to help adults with obesity or overweight lose weight. About 300 people will receive either the drug or a placebo for 40 weeks. The main goals are to see how much weight they lose and if the treatment is safe.

This study tests a 20-week program combining a low-calorie diet with exercise in 70 people who have both obesity and COPD. The goal is to see if weight loss can improve how far they can walk in 6 minutes, as well as their lung function, symptoms, and inflammation. If it works, it…

This study tests whether eating foods high in resistant starch (a type of fiber) can slow down memory and thinking problems in people who have a high genetic risk for cognitive decline. Seventy adults aged 40 and older with obesity or large waistlines will eat either high-resista…

This study will test a family support model that combines two existing programs: a universal school-based program for all first graders and a targeted program for parents of children with overweight or obesity. Researchers will enroll 126 parents of children aged 6-12 in Sweden t…

This study tests whether taking probiotics can reduce digestive side effects like nausea and diarrhea in people starting weight-loss drugs such as semaglutide or tirzepatide. Fifty adults with obesity will take either a probiotic capsule or a placebo daily for 26 weeks. The goal …

This study will test how accurate 10 different heart rate monitors are in 52 overweight young adults, both at rest and during exercise. The goal is to find the best way to measure heart rate at the point where the body burns the most fat. This is an observational study to gather …