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Probiotics may tame nausea from popular Weight-Loss shots

NCT ID NCT07213323

Not yet recruiting Symptom relief Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking probiotics can reduce digestive side effects like nausea and diarrhea in people starting weight-loss drugs such as semaglutide or tirzepatide. Fifty adults with obesity will take either a probiotic capsule or a placebo daily for 26 weeks. The goal is to see if probiotics help maintain a better quality of life during the first few months of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Probiotics (dietary supplement)
What this could lead to
If it works, this could offer a simple way to reduce nausea and stomach issues from popular weight-loss drugs, helping people stay on treatment longer.
What could go wrong
This is a small, early-stage trial with only 50 people. Probiotics may not help everyone, and the study hasn't started yet, so results are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Digestive System Diseases digestive system disorder Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIGESTIVE DISORDERS OBESITY & OVERWEIGHT

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Lyon Sud

    Pierre-Bénite, 69495, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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