OBESITY & OVERWEIGHT

This study tested a new weekly injection called UBT251 in 205 overweight or obese adults to see if it helps with weight loss. Participants received different doses of the drug or a placebo for 24 weeks. The main goal was to measure the percentage change in body weight, with addit…

This study tested a program called HealthyWE in 60 older adults in Camden, New Jersey, to help them manage their weight and reduce pain. The program included training on healthy eating, staying active, and mental wellness. Researchers measured changes in body mass index and pain …

This study tested three different diets—a traditional Mediterranean diet, a low-carb Mediterranean diet, and a high-protein diet—in 45 adults who are overweight or have obesity. Over 12 weeks, researchers measured changes in weight, body fat, muscle, and blood markers like choles…

This study tested whether a dietary supplement with plant extracts can boost natural appetite-regulating hormones in people with overweight or obesity. Forty adults took either the supplement or a placebo daily for 12 weeks. Researchers measured hormone levels and asked about hun…

This study tested two anesthesia approaches for gastric sleeve surgery in 96 patients. One group received standard opioids, while the other also got ketamine. Researchers measured how much opioid pain medicine patients needed after surgery and their pain levels. The goal was to s…

This study tested a new, custom-made 3D-printed device to hold breathing tubes in place for 66 obese adults. Standard methods often fail because of short necks and extra tissue, causing dangerous tube movement. The new holder is designed to fit each patient's face, and researcher…

This study looked at how a 12-week exercise program affects body composition and metabolism in women who had sleeve gastrectomy surgery at least 3 months earlier. Twenty women participated, doing either aerobic exercise alone or a mix of aerobic and strength training. The goal wa…

This study looked at how two common drugs—rifampin and itraconazole—change the way the body processes VCT220, a new medicine being developed for obesity. Thirty-two healthy adults took VCT220 alone and then with each of these drugs to see if their levels in the blood changed. The…

This study checked how a new experimental drug for obesity, VCT220, interacts with three common medications (repaglinide for diabetes, rosuvastatin for cholesterol, and digoxin for heart conditions). Twenty-four healthy overweight adults took VCT220 alone and then with the other …

This study tested a new scoring system called BARSCORE to predict how much vitamin, mineral, and protein supplementation patients need after bariatric surgery. Researchers analyzed data from over 4,500 patients who had surgery between 2015 and 2021. The goal was to create a simpl…

This completed observational study examined whether semaglutide, a drug used for diabetes and weight loss, improves blood flow in the coronary arteries. Researchers measured coronary flow reserve in 122 diabetic and non-diabetic patients before and after 3 months of treatment. Th…

This completed study looked at how obesity influences the health of tissues around dental implants. Researchers measured gum inflammation and collected fluid samples from 80 adults with implants—half with obesity and half without. They checked for signs of inflammation like probi…