OBESITY & OVERWEIGHT

This study aims to find which of two short breathing tests better prepares overweight and obese ICU patients to have their breathing tubes safely removed. Researchers will randomly assign 100 eligible adults to try either a pressure support ventilation or a T-piece method for one…

This study is testing a new drug called RN3161 to see if it is safe and helps with weight loss. It will be given alone and in combination with an existing weight loss medication, tirzepatide, to adults who are overweight or have obesity. The main goals are to check for side effec…

This study is testing whether a more interactive version of a smartphone app helps people follow their care plan better before and after weight-loss (bariatric) surgery. Researchers will compare the new app version to the standard one in 200 patients. They will measure how well p…

This study is testing a mobile app called FoodTraining, which is designed to help people with obesity, binge-eating disorder, or bulimia nervosa strengthen their self-control around food. Over 4 weeks, participants will use the app alongside their standard treatment. Researchers …

This study is observing whether adding a GLP-1 medication (like Wegovy/Ozempic) to a therapy program works better for people with severe obesity and binge eating disorder than therapy alone. It will follow 80 adults in Norway for a year, tracking their weight, eating disorder sym…

This study is testing if restricting meals to an 8-hour window, either early or late in the day, can improve blood sugar control and heart health in people who are overweight and have prediabetes or type 2 diabetes. It will involve 30 participants who will try both eating schedul…

This study is testing whether a dietary supplement made from plant extracts can help people manage their weight. Researchers want to see if the supplement affects gut hormones that control appetite and feelings of fullness. For 12 weeks, 40 adults with overweight or obesity will …

This study is testing whether an experimental injection called UBT251 can help protect kidney function and reduce body weight in adults who are overweight or obese and have chronic kidney disease. About 180 participants will receive either the UBT251 injection or a placebo (dummy…

This study is testing whether giving overweight teens free fruits and vegetables from a local farm for 8 weeks, along with educational videos, helps them eat healthier and improves their blood pressure and weight. Researchers will track 50 teens to see if they pick up their weekl…

This study aims to understand how the body's hunger signals work in people with obesity who are already taking the weight-loss medication semaglutide. Researchers will give 24 participants an experimental compound (LEAP2) that blocks the 'hunger hormone' ghrelin to see if it furt…

This study is testing whether adding chia or hemp seeds to lunch foods helps people feel fuller and more satisfied after eating. Researchers will serve seed-enhanced meals to 24 adults with overweight or obesity and measure how much they eat and how hungry they feel afterward. Th…

This study aims to understand how taking many different medications affects the health of older adults living with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will follow 2,000 participants aged 65 and older for two years, asking them to co…

This study is looking to see if eating freeze-dried grape powder for 4 weeks can improve gut bacteria, reduce body-wide inflammation, and lower stress in adults with obesity. 50 participants will try both the grape powder and a placebo powder in a random order to compare the effe…