New Weight-Loss drug combo tested in early trial

NCT ID NCT07245771

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new drug called RN3161, alone and combined with the weight-loss drug tirzepatide, in 104 adults with overweight or obesity. The main goals are to check safety and how the body handles the drug. Researchers will also measure weight changes. The study is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

RN3161 (investigational drug) and tirzepatide

What this could lead to

If successful, this could lead to a new weight-loss treatment option for people with overweight or obesity, possibly more effective when combined with existing drugs.

What could go wrong

This is an early-phase trial with only 104 participants, so results may not apply to everyone. The drug could cause side effects or fail to show meaningful weight loss.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Nucleus Network Pty Ltd

    RECRUITING

    Melbourne, Victoria, 3004, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••