Magnetic pulses to the brain could help depressed patients think more clearly
NCT ID NCT07161492
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a non-invasive brain stimulation technique called rTMS can improve cognitive flexibility—the ability to adapt thinking—in people with major depression. 105 participants will receive either active stimulation to two brain areas, active stimulation to one area, or sham (fake) stimulation, over 10 days. Researchers will measure changes in thinking skills, mood, and brain activity using tests and MRI scans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
repetitive transcranial magnetic stimulation (rTMS)
What this could lead to
If it works, this could offer a new, non-invasive way to improve thinking and mental flexibility in people with depression, beyond what antidepressants alone can do.
What could go wrong
This is an early-stage trial with only 105 participants, so results may not apply to everyone. The treatment is short (10 days) and effects may not last long-term.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Xiangya Second Hospital of Central South University
Changsha, Hunan, 410011, China
Contact Phone: •••-•••-•••• Email: •••••@•••••