BREAST NEOPLASMS

This study looked at 140 women with early-stage, low-risk breast cancer to compare two radiation approaches after breast-conserving surgery. One group received radiation to the whole breast, while the other received a shorter course targeting only the tumor area. The goal was to …

This study tested leflunomide, a drug usually used for arthritis, in 17 women with metastatic triple negative breast cancer that had already been treated. The goal was to find a safe dose and see if it could stop or shrink tumors. The drug is taken daily by mouth and works by blo…

This study tested several immunotherapy-based drug combinations in 144 people with advanced hormone receptor-positive, HER2-negative breast cancer that had worsened after initial treatment with CDK4/6 inhibitors. Participants received either standard hormone therapy (fulvestrant)…

This early-stage study tested a new drug called H3B-6545 in 33 Japanese women with a common type of breast cancer (ER-positive, HER2-negative). The main goal was to check the drug's safety and find the right dose. This is not a cure, but a step toward better control of the diseas…

This study looked at how well anti-HER2 drugs work in Egyptian women with HER2-positive breast cancer, an aggressive type. Researchers followed 80 patients to see if single or combination therapy improved survival and safety. The goal was to understand real-world effectiveness in…

This study tested whether adding the drug palbociclib to standard hormone therapy (letrozole) helps slow the growth of advanced breast cancer in Asian women who have gone through menopause and have not had prior treatment for their advanced disease. About 340 women took part. The…

This study looked at whether a fast breast MRI can find cancers that mammograms miss in women who have already been treated for breast cancer with lumpectomy and radiation. About 184 women who had a normal mammogram in the last six months and were at least three years past their …

This study tested whether an AI program called CadAI-B dx helps doctors better detect breast cancer on ultrasound images. Sixteen doctors reviewed 797 breast ultrasound cases (350 with cancer, 447 benign) with and without the AI's help. The goal was to see if the AI improved accu…

This study tested an AI system called Carebot AI MMG to see if it can read mammograms as accurately as human radiologists. Researchers used 222 past mammograms from four screening centers and compared the AI's findings to those of three experienced breast radiologists. The goal w…

This study tested whether angiomammography (a contrast-enhanced mammogram) can predict if breast cancer will fully disappear after chemotherapy, compared to MRI. Researchers followed 67 women with breast cancer to see if a 50% tumor size reduction after two chemo cycles could pre…

This study tested whether injecting a local anesthetic (ropivacaine) during breast cancer surgery could prevent chronic pain that often follows. 260 women having breast-conserving surgery or mastectomy received either the anesthetic or a placebo. The main goal was to see if fewer…

This study tested a special program to help breast cancer patients manage joint and muscle pain caused by hormone therapy. About 289 women took part, receiving either the tailored program or standard care. The program included health education and nursing guidance adapted to each…

This study tested a remote monitoring system called CONTINUUM+ CONNECT in 411 adults with metastatic breast, lung, colorectal, or prostate cancer. Participants used the system at home, with or without nursing support, while others received standard care. The goal was to see if th…

This study looked at 80 people having major breast cancer surgery to see which pain relief method works better: a nerve block injection near the spine (ESPB) or numbing medicine given through an IV (lidocaine). The goal was to see which approach helps patients recover more comfor…

This study looked at whether a home-based exercise program with aerobic and resistance training could improve physical fitness, reduce fatigue, and enhance quality of life for breast cancer patients in Indonesia. Thirty-six patients who had completed primary treatment took part. …

This study looked at whether starting a tailored exercise program before breast cancer treatment helps prevent heart damage and other side effects better than exercising only during treatment. 100 women with early-stage breast cancer participated. The goal is to improve quality o…

This study looked at whether a special 'remission' consultation can improve quality of life for women who finished treatment for early-stage breast cancer. Fifty women who had completed chemotherapy or radiation in the last 6 months took part. Researchers measured their quality o…

This study tested whether a smartphone app can help track side effects in breast cancer patients taking oral chemotherapy. 28 patients with metastatic breast cancer used the app to report symptoms and track calls to their care team. The goal was to see if the app improves monitor…

This study examined 52 breast cancer tumor samples and some blood samples to find unique metabolic patterns. The goal was to better understand different types of breast cancer and discover possible markers for diagnosis or treatment targets. Participants were women who had surger…

This study looked at 729 breast cancer patients who had surgery followed by radiation therapy. Researchers checked their thyroid function before and after radiation to see how many developed an underactive thyroid (hypothyroidism). The goal was to find out which patients are most…

This completed study looked at 684 people with breast cancer to see if those with unstable living conditions (social fragility) are more likely to be diagnosed at a later, harder-to-treat stage. Researchers compared early-stage (good prognosis) and late-stage (poor prognosis) cas…

This study looked at how breast cancer treatment affects sexual health in 25 women with non-metastatic breast cancer. Participants filled out anonymous questionnaires about their sexual function, quality of life, and emotional well-being before and after chemotherapy. The goal wa…

This study involved 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers wanted to see how different surgical and radiation techniques affect breast firmness (fibrosis) and cosmetic outcome. The goal was to find ways to improve appearance and q…

This study looked back at medical records of over 500 women in Gulf countries with advanced breast cancer that was previously labeled as HER2-negative. Researchers re-tested old tumor samples to find out how many actually had a newer subtype called HER2-low. The goal was to bette…

This study tested whether a 3D ultrasound technique called shear wave elastography can accurately predict how breast tumors respond to chemotherapy before surgery. Researchers measured tumor stiffness at several points during treatment in 140 women with locally advanced breast ca…

This study looked at how common BRCA1 and BRCA2 gene mutations are in Hispanic/Latino women with breast cancer. Researchers collected saliva samples and health history from 266 participants to better understand these mutations in this group. No treatment was given—the goal was si…

This study looked at 77 women with breast lesions that only show up on special contrast-enhanced mammograms. Doctors wanted to find out the smallest number of tissue samples needed to make a reliable diagnosis. The goal is to make biopsies more efficient and reduce discomfort whi…

This study looked at why some women have dense breasts on mammograms and why that increases their risk of breast cancer. Researchers collected mammograms, biopsy tissue, and health information from 466 women aged 40-65 over 10 years. The goal was to understand what makes breast t…

This study looked at how doctors in Poland treat a common type of advanced breast cancer (HR+/HER2-). Researchers tracked 440 patients to see which treatments were used and how they changed over a year. The goal was to understand real-world care, not to test a new drug.