BREAST NEOPLASMS

This study tested several immunotherapy-based drug combinations for people with advanced HR-positive, HER2-negative breast cancer that had worsened despite standard hormone therapy. It involved 144 participants who received different combinations of drugs, including a standard ho…

This early-stage trial tested a daily pill called leflunomide in women with metastatic triple negative breast cancer (TNBC), a hard-to-treat form of the disease. The study first aimed to find a safe dose and then to see if the drug could help control the cancer. It involved 17 wo…

This study compared two radiation approaches for early-stage breast cancer patients who had breast-conserving surgery. Researchers tested whether a shorter, more targeted radiation treatment (partial breast) caused fewer side effects than the standard whole breast radiation. The …

This study followed 80 Egyptian women with HER2-positive breast cancer to see how well anti-HER2 drugs work in real-world treatment. Researchers observed patients receiving either single drugs or drug combinations as part of their standard care, tracking survival, side effects, a…

This study tested if adding a new drug called palbociclib to a standard hormone therapy (letrozole) was better at controlling advanced breast cancer than the standard therapy alone. It involved 340 Asian, postmenopausal women whose cancer had spread and who had not yet received t…

This study tested a new drug called H3B-6545 in Japanese women with a specific, hard-to-treat type of advanced breast cancer. The main goal was to check if the drug was safe and well-tolerated in this group, and to find a suitable dose. It involved 33 women whose cancer had progr…

This small pilot study tested whether a smartphone app could help patients with metastatic breast cancer better manage the side effects of their oral chemotherapy pills. The goal was to see if the app improved communication with their healthcare team by tracking symptoms and redu…

This study tested whether an artificial intelligence (AI) system could read mammograms as accurately as experienced radiologists. Researchers looked back at 222 anonymized mammograms from four screening centers, comparing the AI's findings against those of three radiologists. The…

This study tested whether an AI software tool called CadAI-B Dx helps doctors interpret breast ultrasound scans more accurately. Sixteen doctors reviewed 797 patient scans, first without the AI and then with its assistance, to see if it improved their ability to correctly identif…

This study aimed to improve a specialized breast biopsy procedure. When a suspicious spot is seen only on a special contrast mammogram, doctors need to take tissue samples. Researchers worked with 77 women to find the minimum number of samples needed to get a reliable diagnosis, …

This study tested whether a special type of mammogram called angiomammography can predict how well a breast tumor will respond to chemotherapy given before surgery. Researchers compared it to MRI scans in 67 women with breast cancer to see which method could better identify early…

This study tested whether a special 3D ultrasound scan, called Shear Wave Elastography, could accurately predict how well chemotherapy was shrinking tumors in patients with locally advanced breast cancer before their surgery. Researchers followed 140 patients, measuring changes i…

This study tested if a faster, shorter type of breast MRI could find cancers that regular mammograms miss in women who had been treated for breast cancer in the past. It involved 184 women who had a normal mammogram result but were at higher risk for the cancer coming back. The g…

This study compared two methods for managing pain after major breast cancer surgery. Researchers tested whether an intravenous lidocaine drip works as well as an ultrasound-guided nerve block injection for helping patients recover comfortably. The trial involved 80 women undergoi…

This study tested whether starting a tailored exercise program before breast cancer treatment begins could better protect the heart and reduce treatment side effects compared to starting exercise during treatment. It involved 100 women recently diagnosed with breast cancer. Resea…

This study looked at 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers compared different combinations of surgical and radiation techniques to understand which approaches lead to less scarring and better cosmetic results. The goal was to hel…

This study tested whether a 12-week home exercise program could help breast cancer survivors in Indonesia feel better. Researchers worked with 36 patients to see if supervised aerobic and resistance training could improve their fitness, reduce tiredness, and boost quality of life…

This study tested whether injecting a local anesthetic (ropivacaine) during breast cancer surgery could prevent long-term pain in the breast area. It involved 260 women who had surgery for breast cancer. Researchers compared the anesthetic injection to a placebo to see which grou…

This study tested a special 'remission' consultation for breast cancer survivors who recently finished their main treatments. Researchers followed 50 patients for a year to see if this consultation improved their quality of life, body image, and ability to return to work. The goa…

This study tested whether a remote monitoring app could improve quality of life for people with advanced cancer. It involved 411 adults with metastatic breast, lung, colorectal, or prostate cancer. Researchers compared patients using the app to report symptoms from home against p…

This study looked back at medical records to understand how common a specific subtype of breast cancer called 'HER2-low' is in the Gulf region. Researchers reviewed records of 517 women with advanced breast cancer to count cases and describe patient experiences. The goal is to ga…

This study aimed to better understand the biology of different types of breast cancer by analyzing the small molecules (metabolites) inside tumor cells. Researchers examined 52 frozen tumor samples from a biobank to look for unique metabolic patterns that could serve as future bi…

This study aimed to understand how breast cancer treatments affect patients' sexual health and quality of life over time. Researchers followed 25 women with non-metastatic breast cancer for one year after starting chemotherapy. They used repeated anonymous questionnaires to track…

This study aimed to understand if a person's social and economic situation is linked to how advanced their breast cancer is when first diagnosed. Researchers compared 684 women with early-stage cancer to those with later-stage cancer. They looked at factors like income, housing, …

This study aimed to understand how often breast cancer patients develop an underactive thyroid (hypothyroidism) after receiving radiation therapy following surgery. Researchers followed 729 patients, checking their thyroid hormone levels before and after treatment to see if the r…

This study aimed to gather information to better understand the links between specific gene changes (BRCA1 and BRCA2) and a harder-to-treat type of breast cancer in Hispanic/Latina women. Researchers collected saliva samples and health history questionnaires from 266 women who ha…

This study aimed to understand why women with dense breast tissue on mammograms have a higher risk of breast cancer. Researchers enrolled 466 women aged 40-65 who were scheduled for a breast biopsy. They collected tissue samples, health data, and tracked participants' health for …