New ultrasound technique may predict chemo response in breast cancer

NCT ID NCT02834494

Completed Diagnosis Sponsor: Institut Curie Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special 3D ultrasound technique, called shear wave elastography, can predict how well breast cancer responds to chemotherapy before surgery. Researchers measured tumor stiffness in 140 women with locally advanced breast cancer at several points during treatment. The goal was to see if changes in stiffness could accurately forecast the final response, potentially reducing the need for extra biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 3D Shear Wave Elastography (ultrasound imaging)
What this could lead to: If successful, this imaging technique could help doctors quickly see if chemotherapy is working, allowing them to adjust treatment earlier.
What could go wrong: This is a completed observational study, not a treatment trial. The imaging method may not be accurate enough to replace standard biopsy or may not work for all tumor types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST NEOPLASMS

Contacts and locations

Locations

Institut Curie Paris

Paris, 75005, France

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