BREAST NEOPLASMS

This study aims to find the best order to use two newer, targeted breast cancer drugs (called ADCs) after standard first-line treatment stops working. It will enroll 40 adults with advanced HR+/HER2- breast cancer whose cancer has progressed on prior therapy. Researchers will com…

This study is testing a personalized approach for people with intermediate-risk, hormone-positive breast cancer. It uses a special blood test to check for tiny signs of cancer. If the test is positive, patients add a targeted drug (CDK4/6 inhibitor) to their standard hormone ther…

This study is testing a new breast cancer medication called imlunestrant in premenopausal women with early-stage, hormone-sensitive breast cancer. Researchers will compare how it affects cancer cells and ovaries to the standard drug tamoxifen. The trial includes two groups: one r…

This study is testing a new smartphone app designed to help breast cancer patients manage the difficult side effects of chemotherapy. The app provides personalized advice based on the patient's reported symptoms and medical guidelines. Researchers will see if patients and nurses …

This study aims to find the most effective combination of support methods to help breast cancer survivors return to their normal work, social, and daily activities after treatment. Researchers will test three different approaches—helping survivors identify their priorities, provi…

This study is testing a program designed to help breast cancer patients in Ethiopia who experience joint pain, stiffness, and fatigue from their hormone therapy. The program, adapted from one used in China, combines home exercises, education, and symptom tracking. Researchers wil…

This study tests whether adding a special surgical material called SureDerm during breast-conserving cancer surgery leads to better cosmetic results and is safe. Researchers will compare two groups of women: one receiving the material and one having standard surgery. The main goa…

This study aims to see if a special fitness and nutrition program can help women newly diagnosed with breast cancer better handle their cancer treatments. It will test if supervised exercise and personalized diet advice, started before treatment and continued at home, can reduce …

This study is testing whether listening to a short daily audio recording of positive self-affirmation statements can help reduce pain, depression, anxiety, and stress in women recovering from mastectomy surgery. It will compare 42 patients who listen to the recording against thos…

This study aims to understand why many breast cancer patients experience severe diarrhea while taking the drug abemaciclib. Researchers will compare the gut bacteria of 60 patients who get diarrhea with those who don't, using stool and blood samples. The goal is to learn if the b…

This study aims to better understand how the body heals after breast reconstruction surgery. Researchers will measure inflammation and stress markers in the blood of 30 women undergoing a specific reconstruction procedure. By tracking these markers before and after surgery, they …

This study aims to observe how the breast cancer drug Talzenna performs in real-world clinical practice in Korea after its approval. It will follow 600 patients already scheduled to receive Talzenna to monitor its safety and effectiveness. This is an observational study, meaning …