ALCOHOL USE DISORDER
Clinical trials for ALCOHOL USE DISORDER explained in plain language.
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Magic mushroom compound shows promise in cutting alcohol cravings
Disease control CompletedThis study tested whether a single high dose of psilocybin, given with psychological support, could help people with alcohol use disorder drink less. Sixty adults from Denmark took part. The main goal was to see if the treatment reduced the number of heavy drinking days over the …
Matched conditions: ALCOHOL USE DISORDER
Phase: PHASE2 • Sponsor: Anders Fink-Jensen, MD, DMSci • Aim: Disease control
Last updated Apr 29, 2026 02:24 UTC
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Future-Thinking training cuts alcohol cravings in lab study
Disease control CompletedThis study tested a technique called Episodic Future Thinking (EFT), where people imagine positive future events in detail, to see if it helps those with alcohol use disorder drink less. 154 adults who wanted to cut down on drinking participated. The approach aims to reduce impul…
Matched conditions: ALCOHOL USE DISORDER
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Disease control
Last updated Apr 29, 2026 02:23 UTC
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Virtual alcohol treatment shows promise in pilot study
Disease control CompletedThis study tested a 4-week virtual intensive outpatient program for people with moderate to severe alcohol use disorder. 63 participants joined from home, using daily breathalyzer checks and online group therapy. The goal was to see if people would stay in the program and find it…
Matched conditions: ALCOHOL USE DISORDER
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated Apr 29, 2026 02:23 UTC
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App-Based therapy plus medication shows promise for alcohol addiction
Disease control CompletedThis study tested a smartphone-based program that combines cognitive-behavioral therapy (CBT) with medication (naltrexone) to help adults with moderate to severe alcohol use disorder reduce their drinking. About 242 employed adults with health insurance participated, and the prog…
Matched conditions: ALCOHOL USE DISORDER
Phase: PHASE2, PHASE3 • Sponsor: Quit Genius • Aim: Disease control
Last updated Apr 29, 2026 02:22 UTC
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New drug shows promise in curbing alcohol cravings
Disease control CompletedThis study tested a medication called GET73 in 79 adults with moderate to severe alcohol use disorder who were not seeking treatment. Participants took GET73 or a placebo for 8 days and had MRI scans to measure brain chemistry and activity. The goal was to see if GET73 could redu…
Matched conditions: ALCOHOL USE DISORDER
Phase: PHASE1, PHASE2 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Apr 29, 2026 02:22 UTC
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New alcohol use disorder drug passes early safety check in healthy drinkers
Disease control CompletedThis early-stage trial tested the safety and tolerability of a new drug called DCR-AUD in 16 healthy adults who drink alcohol socially. Participants received multiple doses of the drug or a placebo and were monitored for 24 weeks, including up to 10 alcohol challenge sessions. Th…
Matched conditions: ALCOHOL USE DISORDER
Phase: PHASE1 • Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC
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Can better sleep reduce heavy drinking? online therapy shows promise
Symptom relief CompletedThis study tested an online insomnia treatment (SHUTi) in 113 heavy drinkers who also had sleep problems. The goal was to see if improving sleep could help reduce alcohol use. Participants used a web-based program to learn better sleep habits, and researchers tracked their drinki…
Matched conditions: ALCOHOL USE DISORDER
Phase: NA • Sponsor: Jessica Weafer • Aim: Symptom relief
Last updated Apr 29, 2026 02:23 UTC
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Can a video-call brain workout help veterans with alcohol recovery?
Knowledge-focused CompletedThis study tested whether an 8-week cognitive training program delivered via telehealth is practical and well-liked by veterans recovering from alcohol use disorder. Nineteen veterans with mild memory or thinking concerns participated. The goal was to see if the program could be …
Matched conditions: ALCOHOL USE DISORDER
Phase: NA • Sponsor: Portland VA Medical Center • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:23 UTC
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Drunk patients Can't guess their BAC, study finds
Knowledge-focused CompletedThis study looked at 34 people who came to the emergency department with alcohol intoxication. Researchers asked them to guess their blood alcohol concentration (BAC) and then compared that guess to a real breath or blood test. The goal was to see if people underestimate how drun…
Matched conditions: ALCOHOL USE DISORDER
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:23 UTC
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Beer before weed? study reveals how order changes intoxication
Knowledge-focused CompletedThis study looked at how combining alcohol with high-THC cannabis concentrates affects people. 146 heavy drinkers who also use cannabis regularly took part. They drank alcohol and used their own cannabis product in a mobile lab, then had their blood drawn, breath tested, and comp…
Matched conditions: ALCOHOL USE DISORDER
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:23 UTC
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Home health visitors boost outcomes for moms and kids in rural south africa
Knowledge-focused CompletedThis study looked at whether community health workers making home visits can improve the health of pregnant women and their babies in a rural area of South Africa. About 1,490 women took part, with some areas getting the home visit program and others not. The researchers tracked …
Matched conditions: ALCOHOL USE DISORDER
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC