Broccoli sprout supplement may shield gut from alcohol damage

NCT ID NCT05902754

Completed Disease control Sponsor: Louisiana State University Health Sciences Center in New Orleans Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a broccoli sprout extract supplement could improve gut health in older adults (50+) who drink at least 8 alcoholic drinks per week and have a low-quality diet. Over 28 days, 40 participants took either the supplement or a placebo. The goal was to see if the supplement could reduce gut leakiness and lower inflammation, which are linked to alcohol-related health problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: broccoli sprout extract (sulforaphane)
What this could lead to: If it works, this could point toward a simple dietary supplement to help protect the gut from damage caused by alcohol and poor nutrition.
What could go wrong: This was a small, early study with only 40 participants, so results may not apply to everyone. The supplement is generally safe, but it may not be strong enough to reverse long-term damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

alcohol abuse Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL USE DISORDER

Contacts and locations

Locations

Louisiana Health Sciences Center

New Orleans, Louisiana, 70112, United States

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