Emergency room could be the starting point for alcohol addiction treatment
NCT ID NCT05827159
First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time
Summary
This study tests whether giving people with moderate to severe alcohol use disorder a medication called naltrexone (as a pill or injection) right in the emergency department, along with a brief counseling session, helps them follow up with ongoing treatment. All participants receive counseling and a referral, but only some get the medication started in the ED. The main goal is to see if more people engage in alcohol treatment 30 days later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- naltrexone (pill or injection) plus a brief counseling session
- What this could lead to
- If successful, this approach could make it easier for people with alcohol use disorder to start treatment right when they are in the emergency department, potentially reducing heavy drinking.
- What could go wrong
- This is a single trial with 240 participants, and the benefits may not apply to everyone. Naltrexone can cause side effects like nausea or headache, and some people may not respond to the medication.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Yale New Haven Hospital
RECRUITINGNew Haven, Connecticut, 06520, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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