Dental pulp necrosis

This trial tests four methods of activating the cleaning liquid during root canal treatment in adults aged 20 to 40 with an infected lower first molar. The goal is to see which method helps the infection at the root tip heal best after 12 months. Participants receive one-visit ro…

This study tests two treatments made from a child's own blood—concentrated growth factor (CGF) and platelet-rich fibrin (PRF)—to help regrow the roots of a damaged permanent molar. Sixty children with an immature, infected lower first molar will receive one of the two treatments …

This study tests whether placing omega-3 fatty acids inside a damaged tooth can help it regrow root length and dentin, compared to the standard method of inducing bleeding. Twenty patients aged 6 to 28 with immature permanent teeth that have died due to injury or decay will be tr…

This study compares two treatments for infected baby molars in children aged 3 to 8: a less invasive method using a triple antibiotic paste versus a standard root canal with a calcium hydroxide-iodoform paste. The goal is to see which approach better relieves pain, swelling, and …

This study compares two materials—enamel matrix derivative and amniotic membrane—to standard blood-clot therapy for regenerating roots of non-vital immature permanent front teeth in children aged 7 to 12. The goal is to see which approach best promotes root growth, closes the ope…

This study tests whether a new nano-based paste (chitosan-coated silver nanoparticles) works better than a standard antibiotic paste for treating infected baby molars in children aged 4-8. The goal is to reduce pain, swelling, and infection, and to see which paste kills bacteria …

This study compares four different rinsing tools used after root canal treatment to see which one reduces pain the most. Fifty-two adults with an infected lower back tooth will be randomly assigned to one of four groups. They will rate their pain at several times over two days an…

This study looks at two ways to clean root canals (rotary vs. reciprocating files) and whether rinsing with very cold saline (cryotherapy) reduces pain after the procedure. Sixty adults with infected but painless teeth will be randomly assigned to one of four groups. Patients wil…

This study tests two ways to clean a tooth during a root canal: laser-activated irrigation and passive ultrasonic irrigation. Researchers want to see which method leads to less pain and better quality of life afterward. 90 adults with infected or damaged permanent teeth are takin…

This study tests whether adding tiny antibacterial particles called mesoporous silica nanoparticles to standard root canal medication can reduce pain and kill more bacteria. Forty-two adults with infected lower molar teeth will receive one of three treatments: standard medication…

This study tests two medications—Chlorhexidine gel and Nitrofurantoin paste—placed inside the tooth during root canal treatment to see which one reduces pain between visits better. 220 patients with infected teeth will report their pain levels before treatment and again after 24 …

This study looked at whether having more frequent contact with a clinician (at least once a week) improves satisfaction for people with long-lasting musculoskeletal conditions. Participants were split into two groups: one with standard contact and one with extra check-ins via tex…

This study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…

This study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …

This study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…

This study measures how hot the inside of a tooth gets when dentists shave off a tiny bit of enamel (a common step before braces). Researchers will test two different tools on 40 teeth from 30 people to see which method causes less heat. Keeping the tooth cool is important becaus…