Could tooth enamel proteins or amniotic membrane save Children's teeth?
NCT ID NCT07252167
First seen Jan 11, 2026 · Last updated Jun 23, 2026 · Updated 25 times
Summary
This study tests two materials—enamel matrix derivative and amniotic membrane—to see if they help regrow root tissue in children aged 7-12 with damaged, immature front teeth. The goal is to improve tooth healing and reduce the need for extraction. The trial involves 39 participants and uses advanced 3D imaging to measure changes in root length and other factors over 12 months.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Al Azhar university
Cairo, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
enamel matrix derivative and amniotic membrane
What this could lead to
If successful, this could offer a better way to help damaged immature teeth regrow root tissue, potentially saving them from extraction.
What could go wrong
This is a small early-phase trial with only 39 participants, so results may not apply widely. The treatments are experimental and may not improve tooth healing compared to standard care.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.