Nanoparticles may ease root canal pain, study hopes
NCT ID NCT07327996
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding tiny antibacterial particles called mesoporous silica nanoparticles to standard root canal medication can reduce pain and kill more bacteria. Forty-two adults with infected lower molar teeth will receive one of three treatments: standard medication, nanoparticles alone, or a mix of both. Pain is measured over 72 hours and bacteria levels are checked before and after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- mesoporous silica nanoparticles combined with calcium hydroxide
- What this could lead to
- If it works, this could lead to a more effective root canal treatment that causes less pain and reduces infection.
- What could go wrong
- This is a small, early-stage trial with only 42 people, so results may not apply to everyone. The nanoparticles are new and their long-term safety is unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Future University in Egypt
Cairo, New Cairo, 11835, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.