Could melatonin be the new toothache soother?

NCT ID NCT07495605

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a 1% melatonin gel to a standard calcium hydroxide paste placed inside the tooth after root canal cleaning. It aims to see which one better reduces pain, lowers bacteria, and affects a certain protein linked to healing. The trial will involve 50 adults with a dead nerve in a lower premolar tooth.

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Conditions

The condition(s) this trial relates to.

dental pulp necrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••