Could melatonin be the new toothache soother?
NCT ID NCT07495605
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a 1% melatonin gel to a standard calcium hydroxide paste placed inside the tooth after root canal cleaning. It aims to see which one better reduces pain, lowers bacteria, and affects a certain protein linked to healing. The trial will involve 50 adults with a dead nerve in a lower premolar tooth.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for INTENSITY OF POSTOPERATIVE PAIN, BACTERIAL LOAD REDUCTION AND PERIAPICAL MMP-9 LEVELS IN PATIENTS WITH NECROTIC PULP are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.