Which tooth medication eases root canal pain better? new trial aims to find out
NCT ID NCT07198919
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two medications—Chlorhexidine gel and Nitrofurantoin paste—placed inside the tooth during root canal treatment to see which one reduces pain between visits better. 220 patients with infected teeth will report their pain levels before treatment and again after 24 and 48 hours. The goal is to help dentists choose the most effective option for patient comfort.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Chlorhexidine gel and Nitrofurantoin paste
What this could lead to
If it works, this could help dentists choose a better medication to reduce pain between root canal appointments, making treatment more comfortable for patients.
What could go wrong
This is an early-phase study with a moderate number of participants. Results may not apply to all patients, and pain relief may vary. No serious risks are expected, but individual responses differ.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AIDM
Karachi, Sindh, 74500, Pakistan