Can your own blood save a tooth? new study tests two natural gels for root regrowth

NCT ID NCT07460869

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two treatments made from a child's own blood—concentrated growth factor (CGF) and platelet-rich fibrin (PRF)—to help regrow the roots of a damaged permanent molar. Sixty children with an immature, infected lower first molar will receive one of the two treatments during a root canal-like procedure. The goal is to see which gel works better at promoting root growth and saving the tooth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

concentrated growth factor (CGF) and platelet-rich fibrin (PRF) from the patient's own blood

What this could lead to

If successful, this could offer a better way to help children's damaged permanent teeth regrow roots and avoid tooth loss.

What could go wrong

This is a small, early-stage study with only 60 participants, so results may not apply to all children. The treatment may not work as well as hoped, and there is a risk of infection or incomplete root growth.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dental pulp necrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dentistry Minya University

    Minya, Minya Governorate, 2422998, Egypt