Can your own blood save a tooth? new study tests two natural gels for root regrowth
NCT ID NCT07460869
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two treatments made from a child's own blood—concentrated growth factor (CGF) and platelet-rich fibrin (PRF)—to help regrow the roots of a damaged permanent molar. Sixty children with an immature, infected lower first molar will receive one of the two treatments during a root canal-like procedure. The goal is to see which gel works better at promoting root growth and saving the tooth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- concentrated growth factor (CGF) and platelet-rich fibrin (PRF) from the patient's own blood
- What this could lead to
- If successful, this could offer a better way to help children's damaged permanent teeth regrow roots and avoid tooth loss.
- What could go wrong
- This is a small, early-stage study with only 60 participants, so results may not apply to all children. The treatment may not work as well as hoped, and there is a risk of infection or incomplete root growth.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for IMMATURE NECROTIC MANDIBULAR FIRST PERMANENT MOLAR are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Dentistry Minya University
Minya, Minya Governorate, 2422998, Egypt