Zagazig University
Clinical trials sponsored by Zagazig University, explained in plain language.
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New fix for twisted bowel shows promise in High-Risk patients
Disease control CompletedThis study tested a new, less invasive procedure to prevent recurrent sigmoid volvulus (a twisted bowel) in 66 high-risk surgical patients aged 16-80. The procedure, called percutaneous sigmoid fixation, aims to fix the sigmoid colon in place to stop it from twisting again. The m…
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated May 22, 2026 14:05 UTC
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New sandwich mesh technique shows promise for tough lumbar hernias
Disease control CompletedThis study tested a new surgical method called 'sandwich mesh repair' for treating lumbar incisional hernias, which are hard to fix because of nearby bone. Ten adults with primary inguinal hernia received the procedure. The main goal was to see if the hernia came back, and the st…
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Hernia mesh breakthrough: new design cuts pain and recurrence
Disease control CompletedThis study tested a new way of placing a single, lightweight mesh during open inguinal hernia repair in 100 men. The goal was to see if this method reduces long-term pain and hernia recurrence compared to standard techniques. The approach covers all weak spots in the groin area a…
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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Mesh repair during sleeve gastrectomy aims to stop hernia from coming back
Disease control CompletedThis study looked at 20 adults who had weight-loss surgery (sleeve gastrectomy) and also needed hiatal hernia repair. Surgeons used a mesh to strengthen the repair and checked if the hernia came back. The goal was to see if adding mesh helps control the hernia long-term.
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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Stent vs. surgery: new hope for kids with esophageal stricture?
Disease control CompletedThis study tested whether a special stent (normally used in bile ducts) can help children whose esophagus has narrowed, making swallowing difficult. Forty children were randomly assigned to get the stent or standard surgery. The main goal was to see if the narrowing comes back. T…
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Which surgery is better for pilonidal sinus? new study compares recovery and sexual function.
Disease control CompletedThis study compared two surgical methods (Karydakis and Limberg flap) for treating pilonidal sinus, a painful cyst near the tailbone. 352 sexually active adults who also drove a car took part. Researchers measured how each surgery affected sexual function and driving ability afte…
Sponsor: Zagazig University • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Early ferritin levels may flag diabetes risk in pregnancy
Diagnosis CompletedThis study looked at whether measuring ferritin (a protein that stores iron) in early pregnancy can help predict which women will develop gestational diabetes later. Researchers followed 556 pregnant women, checking their ferritin and other iron markers early on. The goal was to …
Sponsor: Zagazig University • Aim: Diagnosis
Last updated May 26, 2026 07:26 UTC
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Blood test may replace surgery for endometriosis diagnosis
Diagnosis CompletedThis study looked at whether measuring certain molecules in the blood (microRNAs) can accurately diagnose early-stage endometriosis, a painful condition that can cause infertility. Researchers compared the blood test results to the standard surgical method (laparoscopy) in 60 wom…
Phase: NA • Sponsor: Zagazig University • Aim: Diagnosis
Last updated May 19, 2026 11:46 UTC
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Can melatonin calm surgery stress as well as heart drugs?
Symptom relief CompletedThis study tested whether a simple melatonin pill could reduce stress from breathing tube placement and improve surgical conditions during sinus surgery, compared to two common heart medications. 112 adults undergoing elective sinus surgery were randomly assigned to receive melat…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:59 UTC
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Nerve block breakthrough eases rib fracture pain and improves lung function
Symptom relief CompletedThis study tested two types of ultrasound-guided nerve blocks to see which one better controls pain and helps lung function in people with multiple broken ribs. 50 adults with at least three rib fractures received one of the two blocks. The goal was to improve breathing and reduc…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:59 UTC
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New study tests safer bleeding control for cesarean scar surgery
Symptom relief CompletedThis study looked at 30 women having laparoscopic surgery to fix a cesarean scar niche, a pocket in the uterine wall. It compared injecting a drug called vasopressin into the uterus versus temporarily clamping the uterine arteries to reduce bleeding during the operation. The goal…
Phase: PHASE2 • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:58 UTC
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New pain combo may reduce opioids after hip surgery
Symptom relief CompletedThis study tested two different painkiller combinations for people having hip surgery. One group received nalbuphine with bupivacaine, the other dexamethasone with bupivacaine, both given as a nerve block. The goal was to see which provided better pain control and reduced the nee…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:57 UTC
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Blood proteins battle stretch marks: which combo wins?
Symptom relief CompletedThis study tested two treatments made from a person's own blood—platelet-rich fibrin (PRF) and platelet-rich plasma (PRP)—alone or with microneedling, to see which works better for stretch marks. Thirty adults received different treatments on each side of their body over five ses…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:56 UTC
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Cheaper drug may improve sinus surgery outcomes by reducing bleeding
Symptom relief CompletedThis study tested two drugs, dexmedetomidine and nitroglycerin, to see which better reduces bleeding and improves the surgeon's view during sinus surgery. 66 adults having elective sinus surgery under general anesthesia took part. The goal was to find a more effective and cost-ef…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:56 UTC
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Dietary change brings relief to IBS sufferers
Symptom relief CompletedThis study tested whether a low-FODMAP diet (which limits certain carbohydrates) can reduce symptoms and improve quality of life in people with irritable bowel syndrome (IBS). 183 adults with IBS were split into two groups: one received education on the diet, the other did not. R…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:56 UTC
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Digital support boosts cancer coping skills in new study
Symptom relief CompletedThis study tested an online education and support program to help cancer patients better manage their symptoms and cope emotionally. 212 adults with different cancers (like breast, colon, or lymphoma) who were on chemotherapy took part. The program included online lessons, group …
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:53 UTC
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Nerve block combo calms brain injury storms
Symptom relief CompletedThis study tested two combinations of treatments for 'neurostorm' — a dangerous overreaction of the body's stress system after a traumatic brain injury. 205 critically ill adults received a nerve block (stellate ganglion block) plus either dexmedetomidine or ketamine. The goal wa…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:49 UTC
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One-Week radiation shows promise for breast cancer patients
Symptom relief CompletedThis study tested two different radiation schedules in 60 women with early breast cancer who had breast-conserving surgery. One group received a shorter, more intense course (5 sessions over 1 week), while the other received a standard shorter course (15 sessions over 3 weeks). T…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:49 UTC
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New spray device may replace IV sedation for stomach scope procedures
Symptom relief CompletedThis study tested a new device that sprays numbing medicine in the throat and esophagus, comparing it to standard IV sedation for upper GI endoscopy (a scope procedure to examine the stomach). Sixty adults undergoing elective endoscopy were split into two groups: one received the…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 26, 2026 07:26 UTC
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New study tests better pain relief for obese patients after chest surgery
Symptom relief CompletedThis study tested two methods to control pain after chest surgery in 102 obese patients. One group received a numbing injection near the spine (nerve block), while the other got pain medicine through an IV. The goal was to see which approach worked better and was safer for this s…
Phase: PHASE4 • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Laser precision may tame tricky cataracts
Symptom relief CompletedThis study tested a selective laser to create a precise opening in the lens capsule during cataract surgery in 24 patients with intumescent (swollen) cataracts. The goal was to see if the laser could make the opening more accurate and reduce complications like tears. Results focu…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC
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New shoulder block technique spares breathing, study finds
Symptom relief CompletedThis study tested two newer nerve block methods for shoulder surgery pain relief that aim to avoid a common side effect: temporary diaphragm paralysis, which can make breathing difficult. 87 adults having shoulder surgery were randomly assigned to receive either the standard bloc…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Spine surgery pain study seeks best combo for faster recovery
Symptom relief CompletedThis study tested whether adding midazolam or fentanyl to a standard epidural painkiller (bupivacaine plus dexamethasone) gives better pain relief after lumbar spine surgery. 100 adults undergoing elective lower back fixation took part. The main goal was to see how long it took b…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 20, 2026 11:53 UTC
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Which surgery for burst abdomen is safer? new study investigates
Knowledge-focused CompletedThis study looked at 252 adults who had surgery to repair a burst abdomen (when a surgical wound reopens). Researchers compared two methods: primary repair (stitching the wound back together) and component separation (a more complex technique). The goal was to see which approach …
Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 26, 2026 08:00 UTC
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Blood markers may predict allergy treatment success
Knowledge-focused CompletedThis study looked at whether certain substances in the blood (sST2 and miR-223) can help doctors know how well a treatment for dust mite allergies will work. 54 people with moderate-to-severe dust mite allergies received a 6-month treatment under the tongue. The goal was to see i…
Phase: PHASE1 • Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 26, 2026 07:56 UTC
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New surgical approach may reduce bile duct injuries during gallbladder removal
Knowledge-focused CompletedThis study tested two different surgical techniques for removing the gallbladder. The goal was to see which method causes fewer bile duct injuries. 300 adults having gallbladder surgery took part. The researchers compared a newer technique that combines artery dissection with a s…
Phase: NA • Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 26, 2026 07:56 UTC
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Chest fluid test may guide ventilator weaning decisions
Knowledge-focused CompletedThis completed study looked at 120 critically ill patients on breathing machines to see if measuring fluid in the chest (thoracic fluid content) could help doctors know when it's safe to remove the machine. The goal was to find a better, non-invasive way to predict weaning succes…
Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 26, 2026 07:50 UTC
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666 patients help settle best appendix stitch method
Knowledge-focused CompletedThis study looked at different methods surgeons use to close the stump of the appendix after removing it in people with complicated appendicitis. It included 666 adults aged 18 and older. The main goal was to see which technique leads to fewer leaks from the closure site.
Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 26, 2026 07:49 UTC
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Frailty may predict return of rectal prolapse in seniors
Knowledge-focused CompletedThis study looked at whether frailty is linked to rectal prolapse coming back after surgery. Researchers followed 342 older adults (age 60+) who had surgery for severe prolapse. The goal was to see if frailty increases the chance of recurrence.
Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 22, 2026 13:55 UTC
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Staples or stitches? study compares two ways to repair the gut in emergencies
Knowledge-focused CompletedThis study looked at 90 people who needed emergency intestinal repair surgery. Researchers compared two methods: using a stapling device versus sewing by hand. They tracked complications like leaks, infections, and recovery time to see if one method was better.
Phase: NA • Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC