Zagazig University

Researchers compare two surgical approaches for primary congenital glaucoma, a rare eye condition in children that raises pressure inside the eye. One group receives a combined operation: nasal goniotomy plus temporal trabeculotomy. The other group receives temporal trabeculotomy…

Researchers compare three weekly GLP-1 receptor agonists, dulaglutide, semaglutide, and tirzepatide, in 159 obese adults, 84 with diabetes and 75 without. Participants receive one of the drugs for 24 weeks. The trial measures changes in body weight, BMI, blood sugar, cholesterol,…

This study looks at whether it is safe to remove the gallbladder at the same time as laparoscopic sleeve gastrectomy (a common weight-loss surgery) in patients who are at high risk due to age, multiple health problems, or increased anesthesia risk. It compares patients who had bo…

This trial compares two common ways to remove an inflamed appendix: open surgery (one larger cut) and laparoscopic surgery (several small cuts). The goal is to see which approach leads to fewer complications after the operation. About 832 people with acute appendicitis are taking…

This trial compares two emergency surgeries for people with serious colorectal conditions: the Hartmann procedure and resection with primary anastomosis. The goal is to see which approach leads to fewer complications after surgery. About 714 patients will take part, and researche…

This study compared two surgical approaches for early-stage cervical cancer: laparoscopic-assisted (minimally invasive) and open abdominal hysterectomy. Sixty women with stage IA1 to IB1 cervical cancer were randomly assigned to one of the two surgeries. Researchers measured surg…

This study looked at 20 adults who had weight-loss surgery (sleeve gastrectomy) and also needed hiatal hernia repair. Surgeons used a mesh to strengthen the hernia fix. The goal was to see if this lowers the chance of the hernia coming back. Results suggest mesh repair may help c…

This study tested two ways to reduce bleeding during laparoscopic surgery to repair a cesarean scar niche, a complication of C-sections. One method uses a local injection of vasopressin to constrict blood vessels, while the other temporarily clamps the uterine arteries. The trial…

This completed trial tested a new mesh design for open inguinal hernia repair in 100 men with primary inguinal hernia. The new mesh is cut to fit the posterior wall of the inguinal canal and covered with a sheath to avoid nerve contact. The main goal was to see if it reduces hern…

This study tested whether a special stent (a small mesh tube) usually used for bile ducts could help children with a narrowed esophagus (food pipe). Forty children were randomly assigned to get either the stent or standard surgery. The main goal was to see how often the narrowing…

This completed study tested whether a shorter, more intense course of radiation (1 week) works as well as the standard 3-week course for women with early breast cancer after lumpectomy. Sixty women were split into two groups to compare side effects, cosmetic results, and cancer c…

This study tested a 'sandwich' mesh repair for lumbar incisional hernias, which are hard to treat due to nearby bone. Ten patients received a double mesh (onlay and sublay) to reinforce the weak area. Researchers tracked hernia recurrence and fluid buildup to see if this techniqu…

This completed trial tested a new procedure called percutaneous sigmoid fixation to prevent recurrent sigmoid volvulus (a twisted bowel). The procedure uses an anchor device to fix the colon in place after untwisting it with a scope. The study included 66 high-risk patients aged …

Researchers test whether adding ketamine to propofol improves sedation for drug-induced sleep endoscopy in adults with obstructive sleep apnea. The procedure lets doctors see where the airway collapses during sleep. Thirty adults receive either propofol alone or propofol plus ket…

This study looked at whether measuring certain molecules in the blood (microRNAs) can accurately detect early-stage endometriosis. Researchers compared the blood test results to the standard surgical diagnosis in 60 women. The goal is to find a non-invasive way to diagnose endome…

This study looked at whether measuring ferritin (a marker of iron stores) in early pregnancy can help predict which women will later develop gestational diabetes. Researchers followed 556 pregnant women, measuring their ferritin and other blood markers early on. The goal was to s…

This study tested whether measuring the fluid in the chest using a non-invasive device can predict if a critically ill patient is ready to have their breathing tube removed. Researchers studied 120 adults on ventilators for more than 48 hours. The goal was to see if this measurem…

Surgeons often take a small piece of tissue from inside the mouth to rebuild the urethra in men with a narrowed urine tube. This leaves a raw patch in the mouth that can be painful and slow to heal. Researchers are testing whether covering that mouth wound with a biological dress…

Researchers compare two ways to prevent pain after day-case surgery: an intravenous mix of paracetamol and tramadol, or a single dose of fentanyl, both given before anaesthesia. The trial enrolls 102 adults aged 21 to 65 with a BMI of 25 to 30 who are scheduled for day-case opera…

Researchers compare two nerve block techniques to manage pain after laparoscopic hysterectomy. One block uses ultrasound to guide an injection into the quadratus lumborum muscle; the other places a block near the superior hypogastric plexus during surgery. The trial measures how …

This trial tests whether an opioid-free anesthesia approach, using dexmedetomidine and ketamine, can control pain after discectomy surgery as effectively as traditional opioid-based anesthesia. About 46 adults undergoing elective lumbar discectomy will be randomly assigned to one…

This study compares two minimally invasive procedures for people with low back pain that radiates into the leg (radiculopathy) and hasn't improved with conservative care. One treatment injects ozone gas into the spinal disc, while the other uses pulsed radiofrequency to deliver e…

This study compares two ultrasound-guided nerve block methods for controlling pain after knee surgery: an adductor canal block combined with infiltration of the back of the knee (IPACK) versus a 4-in-1 block. Researchers measure pain scores, how much extra pain medication is need…

This trial investigates whether a fatty liquid given through a vein can help reverse the effects of spinal anesthesia more quickly after same-day surgery. The study includes 70 adults aged 21–70 undergoing elective procedures like general, urology, gynecology, or orthopedic surge…

This study tested a new device that numbs the throat and esophagus (OPETA) against standard IV sedation with propofol and ketamine for upper GI endoscopy. 60 adults were enrolled to see which method causes less discomfort and has fewer side effects. The goal is to find a safer, m…

This study tested a new way to numb the shoulder for surgery using two nerve blocks instead of one. The goal was to see if it controls pain well while keeping arm strength and breathing normal. Fifty adults having shoulder arthroscopy took part. The approach aims to reduce the ne…

This study tested two drugs, dexmedetomidine and nitroglycerin, to see which one better reduces bleeding during functional endoscopic sinus surgery (FESS). 66 adults having elective FESS were randomly assigned to receive one of the drugs to lower blood pressure and improve the su…

This study tested two treatments made from patients' own blood—platelet-rich fibrin and platelet-rich plasma—with or without microneedling, to see which works better for stretch marks. Thirty adults received different treatments on each side of their body over five sessions. Rese…

This study tested whether taking oral melatonin before sinus surgery could reduce the body's stress response and improve the surgical field, compared to two intravenous drugs (metoprolol and dexmedetomidine) or a placebo. It involved 28 adults undergoing elective functional endos…

This study compared two types of nerve blocks—rhomboid intercostal and sub-serratus block versus thoracic paravertebral block—for pain relief and lung function in 50 adults with multiple rib fractures. The goal was to see which block better improves breathing and reduces pain. Re…

This study tested an online educational program for cancer patients receiving chemotherapy. The program included video sessions, peer discussions, and digital materials to help with symptom management and emotional coping. Researchers compared 212 patients who used the program to…

This study tested two ways to manage pain after video-assisted chest surgery in 102 obese patients. One group received an ultrasound-guided nerve block (erector spinae plane block) with bupivacaine, while the other group got an intravenous painkiller (nalbuphine). The goal was to…

This study tested two different pain-relief mixtures given as a nerve block before hip surgery. One group received nalbuphine plus bupivacaine, the other dexamethasone plus bupivacaine. The goal was to see which combination provided longer pain relief and reduced the need for ext…

This study tested whether adding midazolam or fentanyl to a standard epidural painkiller (bupivacaine plus dexamethasone) improves pain control after lumbar spine fixation surgery. One hundred adults undergoing elective surgery were randomly assigned to receive one of the two add…

This study tested two newer nerve block methods for shoulder surgery pain relief, aiming to avoid a common side effect: temporary paralysis of the diaphragm, the main breathing muscle. 87 adults having shoulder surgery received one of three types of nerve blocks. The researchers …

This study tested a nerve block (stellate ganglion block) combined with either dexmedetomidine or low-dose ketamine to treat 'neurostorm' — a dangerous overreaction of the body's stress system after a traumatic brain injury. The goal was to calm symptoms like high blood pressure,…

This study tested whether a low-FODMAP diet—which limits certain carbohydrates that can cause gas and bloating—can reduce symptoms and improve quality of life in people with irritable bowel syndrome (IBS). 183 adults with IBS were split into two groups: one received education on …

This study compared two surgical methods (Karydakis and Limberg flap) for treating pilonidal sinus, a painful cyst near the tailbone. 352 sexually active adults who also drove took part. The main goal was to see how each surgery affected sexual function and the ability to drive a…

This study tested a special laser device (CAPSULaser) to create a precise opening in the lens capsule during cataract surgery in 24 patients with intumescent cataract, a type of dense cataract that can make surgery tricky. The goal was to see if the laser could make the opening m…

Researchers are studying 116 people with chronic watery diarrhea to see how many actually have microscopic colitis, a gut condition that standard tests often miss. Participants will give blood and stool samples and undergo a full colonoscopy with tissue biopsies from different pa…

Researchers are reviewing records from 60 people with liver cirrhosis and portal hypertension who had colon polyps removed during a colonoscopy. The goal is to see whether bleeding right after the procedure or in the following days happens more often in this group. The study also…

This study surveys over 3,700 medical students and interns across the Middle East to find out how many have gastroesophageal reflux disease (GERD). It also looks at how eating habits, stress, anxiety, and depression relate to GERD and how the condition affects their quality of li…

This study is surveying 4,600 medical students and interns across the Middle East to find out how common internet, gaming, and porn addiction are, and whether these addictions are linked to higher stress, anxiety, and depression. Participants fill out online questionnaires about …

This study looks at whether frailty — a state of reduced strength and physical function — increases the risk of complications after gallbladder removal surgery in people over 60 with acute cholecystitis. Researchers will track patients who undergo open cholecystectomy and record …

This study looked at 300 adults having their gallbladder removed by keyhole surgery. It compared two different surgical methods to see which one caused fewer bile duct injuries. The goal was to find the safest approach for this common operation.

This completed Phase 1 study tested whether two substances in the blood (sST2 and miR-223) can help predict how well patients with dust mite allergies respond to a six-month course of under-the-tongue immunotherapy (SLIT). Fifty-four patients with moderate-to-severe allergic rhin…

This study looked at 90 emergency surgery patients who needed their intestine reconnected. Half had a stapled connection and half had a hand-sewn one. Researchers tracked complications like leaks, infections, bleeding, pain, and hospital stay to see which method worked better.

This study looked at different methods for closing the appendix stump after surgery for complicated appendicitis. Researchers compared how often leaks happened with each technique. The study included 666 adults aged 18 and older with complicated appendicitis.

This completed study from Zagazig University looked at 342 older adults (aged 60 and over) who had surgery for rectal prolapse. The goal was to see if frailty—a measure of overall health and weakness—was linked to the prolapse coming back. The researchers compared two surgical me…

This study looked at 252 adults who had surgery for a burst abdomen (when the belly incision reopens after an operation). Researchers compared two repair methods: primary suture with tension sutures versus component separation with mesh. The goal was to see which approach leads t…