New pain combo may cut opioid use after hip surgery
NCT ID NCT06972654
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two different pain-relief mixtures given as a nerve block before hip surgery. One group received nalbuphine plus bupivacaine, the other dexamethasone plus bupivacaine. The goal was to see which combination provided longer pain relief and reduced the need for extra painkillers. 102 adults having hip surgery took part.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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102 people
The number who actually took part.
- Started
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Apr 2025
- Finished
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Jan 2026
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Patients acceptance. * Age: Adults aged 21-75 years old. * BMI: 25-30 kg/m2 * Sex: both sexes (males or females). * Patients undergoing unilateral hip surgery under spinal anesthesia. * ASA (American Society of Anesthesiologists) physical status classification I, II and Ⅲ.. \*Exclusion criteria: * Patients with contraindications to regional anesthesia (e.g. local or systemic infections, or severe neurological or muscular disorders or patient on anticoagulant). * Allergy to study drugs: bupivacaine or nalbuphine or dexamethasone * Patients with severe cardiovascular, respiratory, renal, or hepatic conditions, uncontrolled diabetes diseases, or those undergoing chronic opioid therapy. * Psychiatric disorders that hinder informed consent or study participation. * history of neurological diseases or conditions that would affect the efficacy of nerve blocks (e.g., neuropathy, spinal cord injury, or history of severe muscle weakness).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculity of medicine, Zagazig university, Zagazig
Zagazig, Egypt
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Other studies related to the condition(s) this trial covers.
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