Zagazig University

This trial tests whether giving a small dose of dexmedetomidine, ketamine, or midazolam before the end of squint surgery can reduce the confusion, crying, and thrashing some children experience when waking from sevoflurane anesthesia. Researchers will compare the three drugs in 9…

This trial tests a new surgical technique for people with tricuspid valve disease, where the valve on the right side of the heart is damaged. Instead of replacing the valve with an artificial one, surgeons will use a piece of the heart's own chamber, called the right atrial appen…

This study compares two procedures for treating grade III spleen injuries in stable patients: laparoscopic splenectomy (keyhole removal of the spleen) and splenic artery embolization (blocking the artery to stop bleeding). Researchers will track complications, recovery time, and …

This study tests whether adding a natural substance called lignin to the usual antibiotic treatment helps more people get rid of H. pylori infection. About 70 adults with a first-time H. pylori diagnosis will take either lignin or a placebo daily for two weeks, alongside standard…

Researchers test whether cutting certain nerves around the heart during open-heart surgery can prevent atrial fibrillation, a common irregular heartbeat after the operation. The trial enrolls 560 adults scheduled for elective open-heart surgery. Half receive standard surgery plus…

This study tests whether placing a gentamicin-soaked collagen sponge inside the chest during heart surgery can prevent surgical site infections in high-risk patients. About 142 people at high risk for infection (older adults, those with diabetes, obesity, or other conditions) too…

This study tests two different nerve blocks—Serratus Posterior Superior Intercostal Plane Block (SPSIPB) and Thoracic Paravertebral Block—to see which better controls pain and reduces opioid use after open chest surgery. 48 adults undergoing lung surgery will receive one of the b…

This trial compares two ultrasound-guided nerve blocks—serratus-intercostal and erector spinae—both using a mix of bupivacaine and dexmedetomidine to control pain after mastectomy. The goal is to see which block reduces the need for morphine and improves pain scores. Seventy wome…

This study compares three different drugs (dexmedetomidine, fentanyl, and magnesium sulphate) used alongside propofol anesthesia for brain surgery. The goal is to see which combination reduces the amount of propofol needed and improves patient outcomes. 108 adults undergoing elec…

This study tests whether a targeted nerve block (retrolaminar block) provides better pain relief after lumbar discectomy than the standard method of injecting pain medicine into the surgical wound. 130 adults having elective single-level herniated disc surgery will be randomly as…

This study compares two types of nerve blocks—genicular nerve block and adductor canal block—for pain relief after total knee replacement. It involves 42 adults over 65 undergoing elective knee surgery. The goal is to see which block provides better pain control and helps patient…

This study compares two minimally invasive procedures to treat chronic pelvic pain: laparoscopic presacral neurectomy and fluoroscopically guided nerve block. Sixty-two adults with pelvic cancer-related pain who still have significant pain despite standard treatment will be rando…

This study tests whether a numbing injection near the glossopharyngeal nerve, combined with topical anesthesia, can help people recover faster after surgery for obstructive sleep apnea. The trial involves 80 adults with moderate to severe sleep apnea who are scheduled for palatop…

This trial compares two surgeries—removing part of the stomach (resection) versus creating a bypass—to relieve blockages in advanced stomach cancer. It includes 63 patients with obstructed tumors. The main goal is to see which procedure better eases symptoms like nausea and vomit…

This study compares two approaches—a nerve block and a sedative drug—to reduce pain and improve the surgical field during trans-nasal endoscopic pituitary surgery. About 69 adults will be randomly assigned to receive either a sphenopalatine ganglion block, dexmedetomidine, or sta…

This study tests a new surgical technique called ultrasound-guided microdochectomy for women with chronic, non-dilated single-duct nipple discharge that hasn't improved with medication. The goal is to stop the discharge and evaluate surgical outcomes like pain and bleeding. Fifte…

This study compares two ultrasound-guided nerve block techniques—retroclavicular infraclavicular block and axillary block—for pain control in 90 obese patients (BMI 30-40) having elbow or forearm surgery. Researchers will measure how long pain relief lasts, how much extra pain me…