West China Hospital

This study is testing whether some rectal cancer patients who respond very well to chemotherapy and radiation can safely avoid surgery. Instead of having their rectum removed, these patients would enter a 'watch-and-wait' program with close monitoring. The goal is to preserve nor…

This early-stage clinical trial is testing a new mRNA vaccine designed to help the immune system fight advanced liver cancer. It is for patients whose cancer has continued to grow despite standard treatments. The study will check if the vaccine is safe and if it can shrink tumors…

This study is testing a combination of four treatments for advanced liver cancer that cannot be removed by surgery. It aims to see if delivering targeted radiation directly to the liver tumor, along with three different drugs, is safe and effective. The goal is to control the can…

This study is testing a new pre-surgery treatment for a type of cancer where the stomach meets the esophagus. Researchers want to see if adding a special, shorter course of radiation to standard immunotherapy and chemotherapy is safe and can help shrink tumors more effectively be…

This study aims to find the best starting dose of a common oral medication, propranolol, to heal painful ulcers in infantile hemangiomas. It will involve 40 children with these ulcerated skin growths. Researchers will compare how quickly the ulcers heal and how well the tumors sh…

This study is testing a combination of two oral drugs, afatinib and palbociclib, for people with advanced esophageal cancer that has returned or spread after prior treatment. The first part aims to find a safe dose, and the second part will see if the combination can shrink tumor…

This early-stage study is testing the safety and effectiveness of combining two drugs, HRS-4642 and nimotuzumab, for people with advanced pancreatic cancer that has returned or spread. It will involve about 20 patients to find the right dose and see if the treatment helps shrink …

This is a very early-stage study to test the safety of a new drug called GV20-0251 in adults with advanced solid tumors that have progressed despite standard treatments. The main goal is to find a safe dose by giving the drug to small groups of patients at different levels. It is…

This study is testing whether adding an experimental drug called DCSZ11 to standard cancer treatments is safe and effective for people with advanced solid tumors that have spread. Researchers will enroll 9 adult patients with specific types of cancer to see how well the combinati…

This study is exploring whether eating a high-fiber diet can help people with solid tumors like colorectal cancer. Researchers want to see if more fiber changes gut bacteria and boosts the body's immune response against cancer. They will enroll 25 patients to check the diet's saf…

This study compares two ways of injecting a fluorescent dye to guide surgeons during minimally invasive liver cancer removal. It aims to see if injecting the dye into an artery is better than the standard method of injecting it into a vein at preventing the cancer from coming bac…

This large, late-stage trial is testing a new combination treatment for early-stage triple-negative breast cancer (TNBC), a type that is harder to treat. It combines a short, intense course of radiation (SBRT) with immunotherapy and standard chemotherapy before surgery. The goal …

This study is testing a new combination treatment for people with a type of stomach cancer that is advanced but hasn't spread to distant organs. The goal is to see if adding a shorter, more intense course of radiation to standard immunotherapy and chemotherapy can shrink tumors e…

This study is testing whether a three-part treatment can better control advanced bile duct cancer that starts in the liver. Researchers will give chemotherapy directly to the liver through an artery, combined with two drugs that work throughout the body. The trial aims to see if …

This is an early-stage study to test the safety and initial effects of a new type of cancer vaccine. The vaccine is made from specially engineered mitochondria—tiny parts inside our cells—designed to train the immune system to attack tumors. It will be given to 12 adults with adv…

This early-stage study is testing a new two-drug combination (GV20-0251 plus sintilimab) given to patients before surgery for head and neck cancer. The main goals are to find a safe dose and see if the treatment can shrink the tumors, which is measured by examining the tissue rem…

This early-stage study is testing a new gene therapy called JWK010 for children aged 5-12 with a specific type of albinism (OCA1). The goal is to see if a single injection into the eye is safe and can help the body produce pigment, which may improve vision and eye structure. Rese…

This study is testing a new surgical technique called the 'Huaxi Tunnel Technique' during thyroid surgery. The goal is to better protect the nerves that control vocal cords, which can be accidentally damaged during surgery leading to hoarseness or breathing problems. Researchers …

This study is testing if adding a low dose of radiation to a combination of targeted and immunotherapy drugs works better than the drugs alone when given before surgery for operable head and neck cancer. The goal is to shrink the tumor more effectively to improve surgical outcome…

This study is testing a new fluorescent dye designed to make liver cancer cells glow under special imaging. Researchers will apply the dye to liver tissue removed during standard cancer surgery to see if it can help identify the exact edges of tumors. The goal is to improve surgi…

This early study is testing a new fluorescent dye designed to help surgeons see liver cancer tumors more clearly during surgery. The dye is injected into the patient's artery before the operation. During surgery, a special camera makes the dye glow, helping the surgeon precisely …

This study is testing whether a combination of Chinese herbal mouthwash and oral solution can reduce the time patients suffer from severe mouth sores caused by radiation therapy for head and neck cancers. The trial involves 128 patients who will use either the herbal treatments o…

This study is testing whether traditional Chinese medicine oral liquids and mouthwashes can help reduce painful mouth sores caused by radiation therapy in head and neck cancer patients. Researchers will compare the herbal treatments against a placebo in 118 participants to see if…

This study is testing whether a skin solution made from American cockroach extract can prevent or reduce painful skin burns caused by radiation therapy. 60 adults with head and neck cancer will apply either the test solution or a placebo cream twice daily during their radiation t…

This study is testing a new treatment for severe skin burns caused by radiation therapy in head and neck cancer patients. Researchers are combining a special gel with gentle light therapy to try to help the skin heal faster and reduce pain. The goal is to provide a better option …

This study is testing a new skin treatment designed to prevent and reduce the severity of painful skin burns (radiation dermatitis) caused by radiotherapy in head and neck cancer patients. The treatment is a gel made from natural amino acids that aims to protect the skin by neutr…

This study is testing if simple, non-drug methods can help people wake up better after surgery. Researchers will see if hearing a familiar voice or receiving gentle touch helps patients wake up faster, feel calmer, and have a smoother recovery. The trial will include 205 adults h…

This study is testing whether a spray made from spirulina (a type of algae) can prevent or reduce the severity of painful mouth sores caused by radiation therapy for head and neck cancer. About 70 patients will use either the spirulina spray or a placebo spray four times a day du…

This study aims to use artificial intelligence (AI) to analyze data from 1,300 heart patients who are at high risk of serious bleeding after receiving a stent (PCI). The goal is to identify which patients are most at risk and to figure out the safest and most effective type and d…

This study follows 300 critically ill children who survived sepsis for five years after leaving the hospital. Researchers want to understand how sepsis affects long-term growth, brain development, survival rates, and quality of life. The study compares these children to similar c…

This study aims to find out if a common technique used to control bleeding during liver surgery increases the risk of developing gallbladder problems later. Researchers will look back at the medical records of 2,000 patients who had liver surgery with their gallbladder left in pl…

This study aims to understand what happens to critically ill patients who stay in intensive care for extended periods. Researchers will follow 459 patients across China who have been in ICU for at least 8 days with serious conditions like organ failure or severe infections. They …