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Immune cell 'Packages' injected into tumors: a new hope for advanced cancer?

NCT ID NCT07563972

First seen May 15, 2026 · Last updated Jun 23, 2026 · Updated 8 times

Summary

This early-stage trial tests whether injecting specially reprogrammed immune cell particles (exosomes) directly into tumors is safe for people with advanced solid tumors who have run out of standard options. Nine adults aged 18-65 will receive four injections over eight weeks. The main goal is to check for side effects, but researchers will also watch for any tumor shrinkage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • West China Hospital, Sichuan University

    RECRUITING

    Chengdu, Sichuan, 610041, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mechanobiologically reprogrammed macrophage-derived exosomes

What this could lead to

If it works, this could point toward a new way to treat advanced solid tumors by reprogramming immune cells to attack cancer.

What could go wrong

This is a very early, small Phase 1 trial with only 9 participants, so safety and effectiveness are not yet known. The treatment is injected directly into tumors, which may not work for all cancer types or locations.

Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.