New study aims to find best dose of heart drug to heal painful baby birthmarks
NCT ID NCT06798363
First seen Jun 27, 2026 · Last updated Sep 21, 2026 · Updated 3 times
Summary
This study looks at how well different starting doses of the oral drug propranolol heal ulcers in infantile hemangioma (a type of birthmark). About 40 children with ulcerated hemangiomas will receive either a standard or higher initial dose. The main goal is to see which dose leads to faster ulcer healing, while also monitoring side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2/3
Runs two stages together: whether the treatment works, then large-scale confirmation.
- Participants
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About 32 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2025
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Up to 1 year
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. all patients with ulcer IH; 2. children with ulcer IH treated with propranolol. Exclusion Criteria: 1\) children with ulcer IH who received other therapeutic interventions were excluded; 2) Children whose families refused to participate in the study; 3) patients with contraindications to oral propranolol, such as allergy to propranolol, severe bradycardia and bronchial asthma; 4) children lost to follow-up during oral propranolol treatment; 5) children unable to oral propranolol or continue to oral propranolol due to other reasons. \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sichuan Women and Children's Hospital
RECRUITINGChengdu, Sichuan, 610045, China
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West China Hospital of Sichuan University
RECRUITINGChengdu, Sichuan, 610041, China
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West China Second University Hospital of Sichuan University
RECRUITINGChengdu, Sichuan, 610066, China
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