West China Hospital

This study tested whether two diabetes medications, metformin and empagliflozin, can safely improve metabolic problems (like fat distribution and blood sugar) in people who received a kidney transplant. 105 adult kidney transplant recipients with good kidney function were randoml…

This early-phase study tested a new approach for people with head and neck cancer that can be removed by surgery. Before surgery, patients received low-dose radiation along with two drugs (tislelizumab and afatinib) to see if the combination is safe and tolerable. Only 9 patients…

This study tested whether teaching patients about proper oral care can prevent mouth sores caused by radiation therapy for head and neck cancer. 150 patients were randomly assigned to receive either standard care or extra oral health education. The main goal was to see if the edu…

This study tested a nurse-led program using early movement, leg-sleeve squeezes, and blood tests to prevent deep vein thrombosis (DVT) in 1286 adults after brain or spine surgery. The program was compared to standard hospital care to see if it lowered clot rates within 30 days. P…

This study tested whether a 12-week nursing program based on the Roy Adaptation Model could improve anxiety, depression, and quality of life in 160 adults who developed facial paralysis after surgery for a large acoustic neuroma. Participants received either the special nursing p…

This study tested whether a 12-week nursing program based on the Roy Adaptation Model (RAM) could improve anxiety, depression, and quality of life in 115 adults who recently had a colostomy. Participants either received RAM nursing (education, support, family training, and follow…

This study tested whether a special nurse-led safety program (HFMEA) could reduce problems during emergency surgery for a sudden brain bleed. 156 adults who needed urgent aneurysm repair were randomly assigned to either usual nursing care or usual care plus the safety checklist. …

This study looked at 100 colorectal cancer patients who had already received immunotherapy. Researchers measured a protein called PHGDH in their tumor samples to see if it was linked to how well the treatment worked or how long patients lived. The goal is to find a way to predict…

This study looked at 44 people with a type of brain tumor called glioma. Researchers used a special MRI scan to see if the swollen brain tissue around the tumor still worked. They then took small samples of that tissue during surgery to check for signs of healthy brain cells. The…

This study looked at 23 people with head and neck cancer who were getting radiation therapy. Researchers measured a substance called CGRP in their blood to see if it changes during treatment and if it is linked to pain. The goal was to learn more about pain during radiation, not …

This study looked at 1,200 people with neurocutaneous syndromes (NF1, TSC, SWS, VHL) in Western China over 20 years. Researchers compared those who received genetic testing, targeted drugs, and coordinated care to those who got standard care. The goal was to see if precision medi…

This study looked at 500 children who had surgery for a rare brain tumor called craniopharyngioma. Researchers used MRI scans to grade damage to a key brain area (the hypothalamus) and checked if higher damage led to more growth hormone problems and thinking or emotional issues. …

This study looked at 600 children who had brain tumor surgery to find out which ones might have long-term thinking or memory problems. Researchers used machine learning to analyze medical records and brain scans from before and after surgery. The goal was to create a tool that he…

This study tested a 12-item checklist that nurses can use to quickly spot patients at high risk for brain complications like bleeding or swelling after a common stroke treatment. Researchers compared 213 patients who were monitored with the checklist to 213 who received standard …

This study looked at 800 children with congenital hydrocephalus (fluid buildup in the brain) to see which surgery works best: a shunt (VPS) or a less invasive procedure (ETV). Researchers used MRI scans and machine learning to predict success and reduce repeat surgeries. The goal…

This study analyzed 450 people with cerebellar gliomas who had surgery to remove their tumors. Researchers wanted to see if the tumor's exact location in the brain and its genetic markers could predict how much of the tumor could be safely removed and how long patients would surv…

This study tested a new teaching method for fourth-year medical students. Instead of just watching videos and reading, half the students used virtual reality (VR) to practice brain anatomy and watched live-streamed surgeries with a chance to ask questions. The goal was to see if …