Checklist could cut risks in brain bleed surgery
NCT ID NCT07315048
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a nurse-led safety program using checklists can reduce complications in patients undergoing emergency surgery for a brain bleed (subarachnoid hemorrhage). 156 adults were randomly assigned to receive either standard nursing care or standard care plus the extra safety program. The program focused on spotting and preventing 12 high-risk problems, such as re-bleeding, high brain pressure, and infections. The goal was to see if this approach lowers the number of nursing-related adverse events within 30 days after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- HFMEA-based nursing-risk programme
- What this could lead to
- If it works, this could make emergency brain-aneurysm surgery safer by preventing common complications like re-bleeding and infections.
- What could go wrong
- This is a small, single-center study testing a behavioral intervention, not a drug. Results may not apply to other hospitals or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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156 people
The number who actually took part.
- Started
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Mar 2022
- Finished
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Apr 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. sSAH confirmed by head CT and/or CT angiography (CTA) or digital subtraction angiography (DSA), with identified intracranial aneurysm; 2. Age 18-75 years; 3. Time from onset to admission ≤72 hours; 4. Undergoing emergency surgical treatment (open aneurysm clipping or endovascular coiling); 5. Hunt-Hess grade I-V; 6. Patient or family consent to participate in the study with signed informed consent. Exclusion Criteria: 1. Traumatic subarachnoid hemorrhage; 2. Concurrent other intracranial diseases (e.g., brain tumors, arteriovenous malformations); 3. Severe cardiac, hepatic, or renal dysfunction; 4. Coagulation disorders; 5. History of psychiatric disorders or cognitive impairment; 6. Pregnancy or lactation; 7. Transfer to another hospital or treatment withdrawal.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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West China Hospital of Sichuan University
Chengdu, Sichuan, China
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Other studies related to the condition(s) this trial covers.