University Of Michigan

This large study is testing whether treating sleep apnea with a CPAP machine shortly after someone has a stroke can help prevent another stroke or heart event and improve recovery. Over 3,000 stroke patients are being randomly assigned to receive either 6 months of CPAP treatment…

This study compares two different surgical membranes used during dental surgery to treat peri-implantitis, which is gum disease that develops around dental implants. Researchers will test a new reinforced PTFE mesh against a traditional collagen membrane to see which helps bone a…

This study is testing a mobile app designed to help people with heart failure better manage their condition. The app tracks health status, vital signs, weight, and medications, and shares this information with doctors. Researchers want to see if using this app helps patients get …

This study aims to see if a synthetic bone graft material works better than natural options for preserving jawbone after tooth extraction. Researchers will compare three types of bone grafts in 45 patients who need a tooth removed and plan to get a dental implant later. The goal …

This study is testing two versions of a remote therapy program delivered via smartphone to help teens and young adults (ages 14-24) who were treated in the emergency room for a violent injury. The goal is to reduce their future involvement in violence, aggression, and related ris…

This study is testing new, stronger ceramic dental crowns that can be made and placed in a single appointment. Researchers will follow 48 patients with damaged or decayed back teeth for five years to see how well these crowns hold up and whether they cause tooth sensitivity. The …

This study is testing whether a tart cherry concentrate drink can help prevent irregular heartbeats (atrial fibrillation) that sometimes occur after heart surgery. It will involve 50 patients aged 50-79 who are having elective mitral valve repair surgery. Researchers will measure…

This study is following children with weak muscles (hypotonia) who have trouble breathing during sleep due to a blocked airway. Researchers are checking if a small, flexible tube placed in the nose helps keep the airway open over the long term, improves sleep quality, and is comf…

This study is testing whether a structured home exercise program, delivered through video calls, can help adults with a rare heart condition called Fontan circulation become less frail and improve their strength and endurance. The program aims to make exercise training more acces…

This study is comparing two popular diets—the DASH diet and a very low-carbohydrate diet—to see which one works better for improving blood sugar control and helping with weight loss in adults with polycystic ovary syndrome (PCOS). About 223 participants will follow one of these e…

This study is testing whether adding peer support helps Black men better manage type 2 diabetes. All 48 participants receive standard diabetes education. Half also get 6 months of monthly support sessions led by trained Black men who also have diabetes, followed by 6 months of gr…

This small pilot study is testing whether adding a personal coach helps older adults with obesity stick to their clinic's weight loss plan. The coach helps patients attend appointments like physical therapy and nutrition counseling, and connect to community resources. Researchers…

This study is testing whether a telehealth program delivered by video or phone can help people with alcohol use disorder start treatment and reduce their drinking. Researchers are comparing this remote program to standard care to see which approach works better. The goal is to fi…

This study is testing a community program called Health Impact 360 to see if it improves heart health, reduces stress, and increases social support for adults in marginalized neighborhoods. Over 300 participants will attend group sessions and track their activity for 16 weeks, co…

This study is testing whether using a simple bedside device during routine doctor visits can help quickly evaluate chronic constipation. Researchers want to see if having this device available makes doctors more likely to order the right tests and treatments. The study involves 1…

This study is testing if adding two extra supports helps people stick with a proven diabetes prevention program. It compares the standard program to one that also pairs participants for mutual support and offers vouchers for healthy foods. The goal is to see if these additions he…

This study tests different combinations of counseling and text message support to prevent suicidal behavior in teenagers after they leave psychiatric hospitalization. Researchers are comparing safety planning sessions with and without follow-up text messages, then adding extra su…

This study is looking at whether a school program called Pathways to Potential helps prevent youth violence. The program places 'success coaches' in Michigan public schools to identify and help with family needs like transportation or unemployment, which can affect school attenda…

This study is testing a special afterschool program called CHAMP-ASP to see if it helps young children become more physically active and improve their health. About 264 children, ages 5 to 8, will participate in the program for 35 minutes a day, 3-4 days a week, for 19 weeks. Res…

This study is testing three different healthy eating approaches to see which best helps overweight adults at risk for colorectal cancer improve their diet and potentially lose weight. 240 participants will follow one of the eating plans for 12 months, with some groups getting ext…

This study is testing two different therapy approaches to help people who have both insomnia and alcohol use disorder. Researchers want to see if improving sleep quality can also help people drink less alcohol while they're in treatment. The study involves 134 participants who ar…

This study is testing whether a natural mineral supplement made from red marine algae, called Aquamin®, can help reduce bad breath. Fifteen adults with self-reported halitosis will take the supplement for 90 days. Researchers will measure changes using a questionnaire about breat…

This study tests whether community health workers can effectively teach pain management skills to older adults with chronic pain. Over 400 primarily African American older adults will receive 7 weeks of phone coaching and mobile tools to learn strategies for coping with pain. Res…

This study tests a community health worker program called RESET, designed to help older adults in Detroit manage symptoms like depression, anxiety, chronic pain, and loneliness. The program involves group telephone calls, a podcast series, and activity trackers. Researchers are c…

This study is testing a new computer training program designed to help young adults with autism spectrum disorder (ASD) improve the social skills needed for work. The program uses interactive lessons and simulated conversations with virtual customers and bosses to practice workpl…

This study aimed to test a tracking device called Care Companion, designed to help family caregivers monitor loved ones with dementia who are at risk of wandering away. The research planned to first check if the system was practical to use, then measure if it actually reduced car…

This small study is testing whether a personalized, virtual yoga coaching program is a practical way to help people with lupus manage their chronic pain. Researchers are working with 15 participants to see if they can successfully recruit people and have them complete the 13-week…

This study is testing a school-based program designed to help children aged 6-12 manage symptoms of anxiety and depression. It teaches coping and emotion regulation skills directly in the classroom, aiming to reach kids who might not have access to traditional mental health care.…

This study is testing whether a 12-week online self-management program can help people with painful chronic pancreatitis. Thirty participants will use a website called PainGuide, which provides weekly lessons and tailored advice based on their symptoms. The main goal is to see if…

This pilot study is testing whether two different approaches—'social prescribing' (connecting people to community activities) and brief cognitive therapy—are practical and acceptable ways to help adults struggling with loneliness and suicidal thoughts. The University of Michigan …

This study is testing a virtual wellness program for teenagers with a complex heart condition called Fontan physiology. The program combines group education with personalized home exercises to see if it can reduce frailty, increase physical activity, and improve quality of life. …

This study is testing whether an online job interview training program can help young adults with autism improve their interview skills and get jobs. About 200 participants will either use the virtual training or continue with their usual services. Researchers will track who gets…

This study is testing whether two brief, remote behavioral programs can help adults with chronic migraine reduce their headache-related disability and symptom severity. 300 participants will be randomly assigned to either an 'Empowered Relief' program, a health education program,…

This study is an online survey asking 2,400 adults aged 65 and older in the US and Australia for their opinions. Participants will read a hypothetical story about a patient and share their thoughts on whether continuing aspirin is safe and helpful. The goal is to better understan…

This study compares four different methods for preparing gum tissue during dental surgery to see which leads to better healing and less pain. Researchers will randomly assign 48 dental surgery patients to have their gum tissue prepared using one of four tools: a special blade, a …

This pilot study is testing an educational tool designed to help people with chronic kidney disease make informed decisions about pregnancy and contraception. About 70 patients will receive either the new educational materials or standard information during their doctor visits. R…

This study aims to understand how changes in certain brain chemicals are linked to walking difficulties, balance problems, and cognitive changes in people with Parkinson's disease. Researchers will perform special brain scans (PET scans) on about 125 participants at the start of …

This study uses special MRI scans to understand how different neck positions affect the flow of cerebrospinal fluid around the brain and spinal cord. Researchers are studying people with Chiari malformations (a condition where brain tissue extends into the spinal canal) to see if…

This research aims to understand how common dementia is among older Mexican Americans compared to non-Hispanic whites in Texas. Researchers are visiting homes to track participants' cognitive health over time and examine what factors might contribute to differences between groups…

This study aims to understand how straining during bowel movements affects hemorrhoid symptoms. Researchers will use a special device to test pelvic floor function in 100 participants with bleeding hemorrhoids. The goal is to identify which patients might benefit from treatments …

This study is testing whether using heart rate monitors and a special system during physical education (PE) classes helps improve children's fitness, physical activity, social skills, and mental well-being. It involves about 970 students in 4th through 7th grades from 17 Michigan…

This study aims to understand the financial burden and stress experienced by patients with liver cirrhosis and their family caregivers. It follows 52 participants and their caregivers for 72 weeks, tracking out-of-pocket medical costs, lost work productivity, and overall financia…

This study looks at how Black and White patients with mild memory problems change their health habits, future planning, and research participation after learning about their Alzheimer's risk through brain scan results. Researchers want to understand if this information helps peop…

This study is testing whether a web-based tool called 'My Health, My Choice' helps people with chronic health conditions (like diabetes or high blood pressure) understand and choose birth control options that are safer for their specific health situation. Researchers will compare…

This study aims to understand if having ICU nurses meet with their former patients after hospital discharge affects the nurses' job satisfaction and feelings of burnout. It involves 10 former ICU patients and 20 of their former nurses, with half the nurses randomly selected to ha…

This study aims to understand if sleep-related breathing problems are different for infants with severe spina bifida who had surgery before birth versus after birth. It will also check if these breathing issues are linked to how a child's thinking and movement skills develop by a…

This early study aimed to check if a new wrist-worn device is safe and easy to use. It planned to test the device on healthy volunteers to gather information before future studies with cancer patients. The main goals were to see if people could use the device properly and to moni…

This study aims to find out if the shape of a dental implant crown under the gumline affects the health of the surrounding bone and gum tissue. Researchers will compare two different crown shapes in 30 participants who already have a dental implant. They will monitor changes in b…