University Of Michigan

This study tests different ways to help people scheduled for major elective surgery drink less alcohol before and after their operation. The goal is to improve surgical recovery and long-term health. About 440 adults who drink at risky levels will receive personalized support thr…

This study tests whether sending personalized text messages at the right time can help inactive young adults increase their physical activity and slow weight gain. About 360 participants will wear an activity tracker for 12 months and receive either personalized messages, random …

This study tests whether telehealth programs can help people manage their alcohol use and improve well-being. About 300 participants will receive either a remote group therapy program or standard care, with follow-up for up to 12 months. The goal is to see if virtual sessions hel…

This study tests whether a man-made bone graft material (carbonate apatite) helps preserve the jawbone after tooth extraction better than grafts from human or cow bone. About 45 adults needing a tooth pulled will receive one of the three graft types. Researchers will measure bone…

This study compares two materials used in surgery to treat gum disease around dental implants: a new reinforced PTFE mesh (RPM) and a standard collagen membrane. About 32 adults with infected implants will receive one of the two materials during a submerged surgical procedure. Th…

This study looks at how well a special nasal tube works over a long period for children with weak muscle tone (hypotonia) who have obstructive sleep apnea. About 40 children who already used the device in earlier studies will continue using it. Researchers will check if the devic…

This study tests new technology-driven programs to help people manage their alcohol use and well-being. The programs focus on setting goals and learning skills to improve health. Researchers want to see if these virtual strategies help more people start and stick with treatment a…

This study tests a program called Health Impact 360 to improve heart health, mental well-being, and social support in adults from marginalized communities. About 328 participants will join group sessions twice a week for 8 weeks, then once a week for another 8 weeks, and track th…

This study tests whether tart cherry concentrate can reduce the risk of a common irregular heartbeat (atrial fibrillation) after heart surgery. About 50 adults aged 50-79 having mitral valve repair will take the concentrate and be monitored for side effects, hospital stay length,…

This study looks at whether using a CPAP machine to treat sleep apnea soon after an ischemic stroke can reduce the risk of another stroke, heart attack, or death within 6 months. About 3,000 adults who had a stroke and have sleep apnea are taking part. The goal is to see if this …

This study compares two diets—the DASH diet and a very low-carb diet—to see which one better helps adults with polycystic ovary syndrome (PCOS) control blood sugar and lose weight. About 223 participants will follow their assigned diet for 12 months. The goal is to find a practic…

This study compares two standard methods for treating severe traumatic brain injury in the ICU. One method monitors only brain pressure, while the other also tracks brain oxygen levels. Researchers want to see if adding oxygen monitoring helps improve recovery and survival. About…

This study tests whether monthly support sessions led by trained Black men with diabetes can help other Black men better manage their type 2 diabetes. All participants receive diabetes education, and half also get 6 months of peer support followed by ongoing group activities. The…

This study looks at three different eating plans to help overweight people at risk for colorectal cancer eat healthier and lose weight. About 240 adults with a family or personal history of colorectal cancer or polyps will follow one of the plans for 12 months. The goal is to see…

This study looks at whether adding a support partner and vouchers for healthy food can help people with prediabetes stick to a diabetes prevention program. About 142 low-income adults will either join the standard program or get extra help from a peer and food vouchers. The goal …

This study tests a program called RESET, led by community health workers, to help older adults in Detroit improve their physical and mental health. About 456 African American adults aged 50 and older with symptoms like depression, anxiety, chronic pain, or loneliness will take pa…

This study tests whether an internet-based job interview training program (Virtual Interview Training) helps autistic youth improve their interview skills and find jobs. About 200 participants will either use the training or continue with their usual services. The goal is to see …

This study looks at whether giving caffeine to adults aged 70 and older after major surgery can lower their risk of postoperative delirium—a state of sudden confusion. Researchers will compare caffeine to a placebo in 250 participants. The goal is to see if this simple, everyday …

This study tests whether a virtual reality (VR) program can help manage pain in people with inflammatory bowel disease (IBD). About 40 adults with IBD and abdominal pain will use a VR headset at home for 4 weeks. The goal is to see if the program is easy to use and acceptable, an…

This study tests whether Aquamin, a natural mineral from red algae, can reduce bad breath. Fifteen adults with self-reported halitosis took the supplement for 90 days. Researchers measured improvement using a questionnaire about how bad breath affects daily life.

This study tests if a cream called imiquimod can shrink sebaceous hyperplasia—small, harmless bumps on the face caused by overactive oil glands. Forty adults with bumps on both sides of their face will use the cream for 8 weeks. Researchers will check how many bumps shrink or dis…

This study tests whether a structured home exercise program, delivered via video calls, can reduce frailty and improve daily activity in adults with Fontan circulation. About 53 participants will follow the program for 6 months. The goal is to make exercise training more accessib…

This study looks at whether a tailored yoga coaching program can help people with lupus manage chronic pain. Researchers will enroll 15 adults with lupus who have had pain for at least 3 months. The program lasts 13 weeks and focuses on gentle, personalized yoga and coaching. The…

This study tests a program called Kids' Empowerment Program (KEP) in schools to help children ages 6 to 12 who struggle with anxiety and depression. About 120 children will take part, with some starting the program right away and others later, so researchers can compare results. …

This study tests a virtual program for teens aged 13-18 with Fontan physiology, a serious heart condition. The program combines group wellness education with a personalized home exercise plan. Researchers want to see if it improves resilience, reduces frailty, and increases daily…

This study looks at whether brief behavioral programs can help adults with chronic migraine. 300 participants will be assigned to one of four groups and take part remotely. The goal is to see if these programs reduce headache-related disability and improve symptoms over several m…

This study tests two treatments for loneliness and suicidal thoughts: Social Prescribing (connecting people with community activities) and Brief Cognitive Therapy (changing unhelpful thinking patterns). Researchers want to see if these treatments are practical and well-liked by 6…

This study tests an 8-week online group program designed to help people with scleroderma improve their thinking skills and overall well-being. Researchers will compare participants who take the program right away to those on a waitlist. The goal is to see if the program boosts me…

This study looks at whether adding heart rate monitors and other technology to physical education classes helps kids be more active, improve their fitness, and build social and emotional skills. About 970 students in grades 4-7 will take part. Researchers will measure activity le…

This study looks at how emotions, attachment, and feeding work together in mothers and babies during the first year of life. Researchers want to understand why some babies gain weight quickly, which can lead to obesity later. About 250 mother-infant pairs will be observed to see …

This study explores how social and financial factors—like income, education, and out-of-pocket costs—affect people with cirrhosis and their caregivers. Researchers will survey participants and their caregivers to measure financial distress and healthcare use. The goal is to bette…

This study looks at different ways to remove the outer layer of gum tissue during dental surgery. About 48 adults will take part to see which method leaves less leftover tissue, heals faster, and causes less pain. The goal is to improve surgical outcomes for patients needing gum …

This study looks at what happens when ICU nurses meet with patients they once cared for, after the patients leave the hospital. Researchers want to see if these meetings improve the nurses' sense of fulfillment and reduce burnout. The study involves 10 former ICU patients and 20 …

This study aims to understand why straining during bowel movements leads to bleeding from hemorrhoids. Researchers will use a special FDA-cleared device to test pelvic floor muscle function in 100 adults who have had recent rectal bleeding. The goal is to find better ways to trea…

This study looks at different technology-based strategies to help teens who have been hospitalized for suicidal thoughts or attempts. Researchers want to find the best combination of tools to reduce the risk of future suicide attempts. About 300 teens aged 12-17 who recently had …

This study looks at breathing problems during sleep in infants with myelomeningocele, a severe form of spina bifida. Researchers compare babies who had surgery before birth versus after birth to see if one group has fewer breathing issues. They also check how these breathing prob…

This study looks at how well a new type of strong ceramic crown holds up over five years. The crowns are made using a computer in a single dental visit, so no temporary crown is needed. About 48 adults with a decayed, broken, or failing filling in a back tooth will get the crown.…

This study aimed to test a tracking device (Care Companion) for family caregivers of people with dementia who are at risk of wandering. It was planned in two stages: first to see if the device was easy to use, and second to check if it helped reduce caregiver stress. However, the…

This study looks at whether a special afterschool program called CHAMP can help children ages 5 to 8 be more physically active and improve their motor skills. About 264 kids will take part in the program or be in a control group for 19 weeks. Researchers will measure changes in a…

This study was designed to test how easy and safe a new watch-like device (Watch-TEA) is to use. It was planned for healthy adults to wear the device for a few days and report any skin irritation or discomfort. The goal was to gather information that could help develop the device…

This study uses MRI scans to see how different neck positions affect the flow of cerebrospinal fluid (the fluid around the brain and spinal cord) in people with Chiari malformations. Researchers will compare results from healthy volunteers and patients to better understand the co…

This study follows 125 people with Parkinson's disease or related conditions over 2 years. Researchers use special brain scans to see how changes in a brain chemical called acetylcholine relate to walking difficulties and thinking skills. The goal is to better understand these pr…

This study looks at how a new bedside device, called the Rectal Expulsion Device (RED), can help doctors evaluate chronic constipation during a regular office visit. About 109 adults with chronic constipation will use the device and complete a survey. The goal is to see if using …

This study looks at how eating behaviors in infancy are linked to diet, growth, and behavior when children reach school age (5-7 years). About 400 children and their parents will take part in food-related activities and questionnaires. The goal is to understand early influences o…

This study looks at how the part of a dental crown that sits under the gums affects the health of the gum and bone around dental implants. Researchers will measure bone loss, gum thickness, and gum height in 30 adults who already have an implant ready for a crown. The goal is to …

This study looks at whether people with mild memory problems change their health habits, make future plans, or join more research after learning their personal Alzheimer's risk from brain scans. It includes 100 Black and White adults with mild cognitive impairment. The goal is to…

This study looks at a Michigan program called Pathways to Potential (P2P) that places caseworkers in schools to help families with needs like transportation or jobs. Researchers want to see if this program lowers youth violence, child abuse, and school absences. They will study d…

This study tests a new educational tool to help people with chronic kidney disease (CKD) make informed decisions about pregnancy and contraception. About 70 participants will use the tool and then answer surveys to see if it helps them feel prepared. The goal is to see if this ap…

This study looks at whether counseling sessions done over video (telehealth) are practical and well-liked by people with substance use disorder who are not currently getting treatment. About 50 participants will try the program and fill out surveys before, during, and after. The …

This small pilot study tested whether a 6-week remote occupational therapy program could help older adults living in affordable senior housing become more physically active. The program used respected residents to encourage participation and included one-on-one and group sessions…

This study tests a free web tool called My Health, My Choice that helps people with health conditions like diabetes or high blood pressure understand their birth control options. About 795 participants will either use the tool before a clinic visit or receive usual care. The goal…