University Of Michigan

This study tests whether adding a digital incentive program to traditional quitline services helps adults who smoke menthol cigarettes quit. About 1,200 participants will use an app that rewards them for check-ins, calls to a coach, and staying smoke-free. The goal is to see if t…

This trial compares three approaches for treating painful diabetic neuropathy: oral medications, topical treatments, and cognitive behavioral therapy. Researchers will enroll 600 adults with diabetes and nerve pain, randomly assigning them to one of these options for four months.…

This study looks at whether a program called HEARTS can help people who have both high blood pressure and diabetes get better care. About 1,440 adults in Guatemala will take part, and clinics will either use the HEARTS program or continue their usual care. The program includes tr…

Researchers are testing whether adding a brain-injury blood test to standard clinical guidelines can safely reduce the number of brain CT scans ordered for adults who come to the emergency department with a suspected head injury. The blood test measures two proteins, GFAP and UCH…

This study tests whether delivering prepared meals or boxes of unprepared food to pregnant people at risk of gestational diabetes is practical and acceptable. Researchers will give participants either ready-to-heat meals from a diabetes-friendly menu or boxes with fresh produce a…

This study tests a new prevention program delivered through social media to help young adults reduce high-intensity drinking and improve wellness. Researchers will enroll 450 people who regularly use Snapchat and have recently engaged in heavy drinking. The goal is to see if this…

This study tests a 12-week group program called Mama Empoderada for Spanish-speaking mothers of young children. The program teaches parenting skills, self-care, and how to build support networks. Researchers hope it will reduce depression, anxiety, and stress while improving moth…

Researchers at the University of Michigan are studying whether a home device called Transcutaneous Electrical Acustimulation (TEA) can help adults with cirrhosis manage chronic pain. The trial enrolls 100 people who report ongoing pain on most days. Participants use either a real…

Researchers at the University of Michigan are testing a remote program for adults with cannabis use disorder. Participants receive six telemedicine sessions that blend motivational coaching with small incentives for staying engaged. The study compares this approach with enhanced …

This study tests an online tool called HOME-MIND designed to help older adults (65+) who live alone and have mild memory or thinking problems manage their medications. Participants use a platform to track medication issues, get personalized tips, and share summaries with their do…

This trial tests a digital program called ConCERN for friends and family members of people with opioid use disorder. The program provides educational modules to reduce stigma, improve communication, and help navigate treatment options. Researchers will measure changes in the supp…

This pilot study tests a culturally adapted empowerment self-defense program for Indigenous women (including American Indian, Alaska Native, and Two Spirit individuals) who have experienced sexual violence and currently have moderate to severe depression or PTSD. The program teac…

This study tests a program called Enlace Familiar, designed to help Latino teenagers ages 14-18 talk about their mental health with parents or trusted adults. The program involves two sessions with a community health worker and a list of mental health resources. Researchers want …

This study tests whether a mobile health program can help people with heart failure increase their physical activity and stay active. The program includes a smartphone app for goal-setting and self-monitoring, an AI-based health coach trained in motivational interviewing, and occ…

This early study tests a robotic leg brace with smart software that senses how a person walks and adjusts its help in real time. Researchers want to see if this adaptive system improves walking speed and balance in stroke survivors compared to a standard brace. About 20 people, i…

This study tests a new, high-dose form of non-invasive brain stimulation (called accelerated theta burst stimulation) to see if it can improve walking problems, like freezing, in people with Parkinson's disease. The study will enroll 20 adults with early-stage Parkinson's who hav…

This study looks at whether mindfulness-based stress reduction can help Black teenage girls who have been involved with the justice system and their parents or caregivers. About 90 participants will report on stress, PTSD symptoms, and other outcomes before and after the program.…

This observational study examines how antiplatelet medications affect platelet function in people over 80 with atrial fibrillation who have received a Watchman implant. Researchers will measure various markers of platelet reactivity before and after treatment to see if clotting r…

This study tests whether using a new risk-prediction model (C-HARP) to assign follow-up phone calls after hospital discharge works better than the current standard method. About 5,000 adults leaving the hospital will be assigned to one of two allocation strategies. The goal is to…

This study will see if an AI chatbot app is practical and acceptable for family caregivers of people with traumatic brain injury, dementia, or Huntington disease. About 60 caregivers will use the app for 8 weeks, focusing on physical and mental health. They will complete surveys …